Strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes
Bicyclo[1.1.0]butanes (BCBs) and [1.1.1]propellanes (tricyclo[1.1.1.01,3]pentanes, TCPs) are structurally unique compounds with different chemical properties. Strain-release driven reactions have emerged as an atom- and step-economic strategy for the organic synthesis. Using this strategy, a variety...
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Published in | Tetrahedron chem Vol. 9; p. 100070 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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Elsevier Ltd
01.03.2024
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Abstract | Bicyclo[1.1.0]butanes (BCBs) and [1.1.1]propellanes (tricyclo[1.1.1.01,3]pentanes, TCPs) are structurally unique compounds with different chemical properties. Strain-release driven reactions have emerged as an atom- and step-economic strategy for the organic synthesis. Using this strategy, a variety of functional ring molecules have been efficiently synthesized, including various cyclobutane molecules, bicyclo[2.1.1]hexanes, bicyclo[1.1.1]pentanes, and others. More specifically, these strain release-driven reactions include aspects of nucleophilic addition, radical addition, electrophilic or transition metal catalysis. This review will discuss the recent developments in the strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes.
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AbstractList | Bicyclo[1.1.0]butanes (BCBs) and [1.1.1]propellanes (tricyclo[1.1.1.01,3]pentanes, TCPs) are structurally unique compounds with different chemical properties. Strain-release driven reactions have emerged as an atom- and step-economic strategy for the organic synthesis. Using this strategy, a variety of functional ring molecules have been efficiently synthesized, including various cyclobutane molecules, bicyclo[2.1.1]hexanes, bicyclo[1.1.1]pentanes, and others. More specifically, these strain release-driven reactions include aspects of nucleophilic addition, radical addition, electrophilic or transition metal catalysis. This review will discuss the recent developments in the strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes. Bicyclo[1.1.0]butanes (BCBs) and [1.1.1]propellanes (tricyclo[1.1.1.01,3]pentanes, TCPs) are structurally unique compounds with different chemical properties. Strain-release driven reactions have emerged as an atom- and step-economic strategy for the organic synthesis. Using this strategy, a variety of functional ring molecules have been efficiently synthesized, including various cyclobutane molecules, bicyclo[2.1.1]hexanes, bicyclo[1.1.1]pentanes, and others. More specifically, these strain release-driven reactions include aspects of nucleophilic addition, radical addition, electrophilic or transition metal catalysis. This review will discuss the recent developments in the strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes. [Display omitted] |
ArticleNumber | 100070 |
Author | Zhou, Ling Chen, Jie Yang, Yang Hu, Qian-Qian Yang, Hui |
Author_xml | – sequence: 1 givenname: Qian-Qian surname: Hu fullname: Hu, Qian-Qian organization: Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, 710127, China – sequence: 2 givenname: Jie surname: Chen fullname: Chen, Jie organization: Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, 710127, China – sequence: 3 givenname: Yang surname: Yang fullname: Yang, Yang organization: Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, 710127, China – sequence: 4 givenname: Hui surname: Yang fullname: Yang, Hui email: yanghui@xust.edu.cn organization: College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an, 710054, China – sequence: 5 givenname: Ling orcidid: 0000-0002-6805-2961 surname: Zhou fullname: Zhou, Ling email: zhoul@nwu.edu.cn organization: Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, 710127, China |
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Keywords | [1.1.1]Propellanes Strain-release transformation Bicyclo[1.1.0]butanes |
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Title | Strain-release transformations of bicyclo[1.1.0]butanes and [1.1.1]propellanes |
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