Oxidative stress in neurodegenerative diseases

• Published in: Neural regeneration research Vol. 7; no. 5; pp. 376 - 385
• Main Authors: Chen, Xueping, Guo, Chunyan, Kong, Jiming
• Format: Journal Article
• Language: English
• Published: India Department of Human Anatomy and Cell Science, University of Manitoba, Manitoba, Canada%Department of Pharmacy, Hebei North University, Zhangjiakou 075000, Hebei Province, China 15.02.2012; Medknow Publications & Media Pvt Ltd
• Subjects: Review; 平衡状况; 氧化应激; 生物活性氧; 神经胶质细胞; 神经退行性疾病; 细胞信号转导; 羟自由基; 酶促反应; neurodegenerative diseases; reviews; therapy; oxidative stress; reactive oxygen species

Reactive oxygen species are constantly produced in aerobic organisms as by-products of normal oxygen metabolism and include free radicals such as superoxide anion （02-） and hydroxyl radical （OH-）, and non-radical hydrogen peroxide （H202）. The mitochondrial respiratory chain and enzymatic reactions b...