Gastrointestinal Motility Effects of GLP-1 Receptor Agonists

• Published in: Current gastroenterology reports Vol. 27; no. 1; p. 49
• Main Authors: Bellavance, Danielle, Chua, Samantha, Mashimo, Hiroshi
• Format: Journal Article
• Language: English
• Published: New York Springer US 07.07.2025; Springer Nature B.V
• Subjects: Agonists; Cardiovascular disease; Cohort analysis; Diabetes; Drug dosages; Esophagus; Gastric Emptying - drug effects; Gastroenterology; Gastrointestinal Motility - drug effects; GLP-1 receptor agonists; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptide-1 Receptor Agonists; Glucose; Humans; Hypoglycemic Agents - adverse effects; Hypoglycemic Agents - pharmacology; Insulin; Medicine; Medicine & Public Health; Metabolism; Motility; Parkinson's disease; Peptides; Weight control; United States > US

Purpose of Review This review summarizes the current understanding of the physiologic influence of GLP-1 RAs on gastrointestinal motility, highlights key clinical implications of these effects, and defines areas for future investigation. Recent Findings Glucagon-like peptide-1 receptor agonists (GLP...