Prevention of oxidative stress, inflammation and mitochondrial dysfunction in the intestine by different cranberry phenolic fractions

• Published in: Clinical science (1979) Vol. 128; no. 3; pp. 197 - 212
• Main Authors: Denis, Marie-Claude, Desjardins, Yves, Furtos, Alexandra, Marcil, Valérie, Dudonné, Stéphanie, Montoudis, Alain, Garofalo, Carole, Delvin, Edgard, Marette, André, Levy, Emile
• Format: Journal Article
• Language: English
• Published: England 01.02.2015
• Subjects: Adenosine Triphosphate - metabolism; Antioxidants - chemistry; Apoptosis; Biflavonoids - chemistry; Caco-2 Cells; Catechin - chemistry; Dinoprostone - metabolism; Fatty Acids - chemistry; Humans; Inflammation - drug therapy; Intestines - drug effects; Lipid Peroxidation; Mitochondria - drug effects; Oxidative Phosphorylation; Oxidative Stress; Plant Extracts - therapeutic use; Proanthocyanidins - chemistry; Vaccinium macrocarpon - chemistry

Cranberry fruit has been reported to have high antioxidant effectiveness that is potentially linked to its richness in diversified polyphenolic content. The aim of the present study was to determine the role of cranberry polyphenolic fractions in oxidative stress (OxS), inflammation and mitochondria...