GLP-1 receptor agonists and MASLD in diabetes: A promising path?

• Published in: Journal of diabetes and its complications Vol. 39; no. 7; p. 109041
• Main Authors: Pennisi, Grazia, Petta, Salvatore, Maggio, Viviana, Rizzo, Manfredi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2025; Elsevier Limited
• Subjects: Agonists; Atherosclerosis; Clinical trials; Diabetes; GLP-1 receptor agonists; Glucagon; Hormones; Insulin resistance; Liver cancer; Liver cirrhosis; Liver diseases; Metabolism; Obesity

Furthermore, the use of GLP-1 agonists was found to significantly reduce the likelihood of fibrosis progression (OR = 0.105, 95%CI = 0.014–0.789, p = 0.028), with protective effects persisting even after adjusting for age, gender, blood sugar, and blood pressure (OR = 0.756, 95%CI: 0.013–0.746, p =...