UCHL1-Mediated Spastin Degradation Regulates Microtubule Severing and Hippocampal Neurite Outgrowth - Ma, Ao; Liang, Zhi; Zhang, Hongde; Meng, Zhichao; Zhu, Jiehao; Chen, Shu; Lin, Qisheng; Jiang, Tao; Tan, Minghui (Journal of molecular neuroscience, 2025)
Keywords: Adenosine Triphosphatases - genetics; Adenosine Triphosphatases - metabolism; Animals; Axonogenesis; Biodegradation; Biomedical and Life Sciences; Biomedicine; Cell Biology; Cells, Cultured; Cytoskeleton; Degradation; Hereditary spastic paraplegia; Hippocampus; Hippocampus - cytology; Hippocampus - metabolism; Humans; Immunoprecipitation; Mass spectrometry; Mass spectroscopy; Mice; Microtubules - metabolism; Neurites - metabolism; Neurochemistry; Neurology; Neuronal Outgrowth; Neurosciences; Paraplegics; Proteasome inhibitors; Proteasomes; Protein gene product 9.5; Proteins; Proteolysis; Proteomics; Rats; Regulatory mechanisms (biology); Spastin - genetics; Spastin - metabolism; Ubiquitin Thiolesterase - genetics; Ubiquitin Thiolesterase - metabolism; Microtubule severing; UCHL1; Protein degradation; Spastin; Neurite outgrowth