Resting-State Perfusion in Nonmedicated Schizophrenic Patients: A Continuous Arterial Spin-labeling 3.0-T MR Study

• Published in: Radiology Vol. 256; no. 1; pp. 253 - 260
• Main Authors: Scheef, Lukas, Manka, Christoph, Daamen, Marcel, Kühn, Kai-Uwe, Maier, Wolfgang, Schild, Hans H., Jessen, Frank
• Format: Journal Article
• Language: English
• Published: United States 01.07.2010
• Subjects: Adult; Analysis of Variance; Brain - blood supply; Brain - diagnostic imaging; Brain Mapping; Case-Control Studies; Cerebrovascular Circulation - physiology; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging - methods; Male; Positron-Emission Tomography; Prospective Studies; Rest; Schizophrenia - diagnostic imaging; Schizophrenia - physiopathology; Spin Labels; Tomography, Emission-Computed, Single-Photon
• ISSN: 0033-8419; 1527-1315; 1527-1315
• DOI: 10.1148/radiol.10091224

To determine whether well-described patterns of altered perfusion in schizophrenia can be identified by using continuous arterial spin labeling (CASL) with a whole-brain imaging sequence. This study was approved by the ethics committee of the local institutional review board, and written informed co...