Reference‐Attached pH Nanosensor for Accurately Monitoring the Rapid Kinetics of Intracellular H+ Oscillations

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 21; no. 3; pp. e2406796 - n/a
• Main Authors: Wen, Ming‐Yong, Qi, Yu‐Ting, Jiao, Yu‐Ting, Zhang, Xin‐Wei, Huang, Wei‐Hua
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.01.2025
• Subjects: Acidification; Biosensing Techniques - methods; biosensors; Cell membranes; Dynamic response; Electric potential; Electrodes; Glycolysis; Homeostasis; Humans; Hydrogen-Ion Concentration; intracellular pH oscillations; Kinetics; metabolism; Monitoring; Nanosensors; Nanotechnology - methods; Nanowires; Nanowires - chemistry; Oscillations; potentiometry; Protons; Time synchronization; intracellular pH oscillations; biosensors; metabolism; potentiometry; glycolysis

Intracellular pH (pHi) is an essential indicator of cellular metabolic activity, as its transient or small shift can significantly impact cellular homeostasis and reflect the cellular events. Real‐time and precise tracking of these rapid pH changes within a single living cell is therefore important....