Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans - Maciejewski, Benjamin S.; LaPerle, Jennifer L.; Chen, Danny; Ghosh, Avijit; Zavadoski, William J.; McDonald, Thomas S.; Manion, Tara B.; Mather, Dawn; Patterson, Terrell A.; Hanna, Maya; Watkins, Steven; Gibbs, E. Michael; et al. (American journal of physiology: Gastrointestinal and liver physiology, 2013)
Keywords: Adolescent; Adult; Animals; Case-Control Studies; Diacylglycerol O-Acyltransferase - antagonists & inhibitors; Diacylglycerol O-Acyltransferase - genetics; Diacylglycerol O-Acyltransferase - metabolism; Dietary Fats - blood; Dietary Fats - metabolism; Dose-Response Relationship, Drug; Enterocytes - metabolism; Enzyme Inhibitors - pharmacokinetics; Enzyme Inhibitors - pharmacology; Fatty acids; Fatty Acids, Unsaturated - blood; Fatty Acids, Unsaturated - metabolism; Female; Humans; Intestinal Absorption - drug effects; Intestinal Mucosa - metabolism; Lipid Metabolism - drug effects; Lipids; Male; Metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Oxazepines - pharmacokinetics; Oxazepines - pharmacology; Pathogenesis; Postprandial Period; Rats; Rats, Sprague-Dawley; Rodents; Triglycerides - blood; Triglycerides - metabolism; Vitamin A; Vitamin A - metabolism; lipid absorption; vitamin A; triglycerides; DGAT1; lipid metabolism