Microparticles as new markers of cardiovascular risk in diabetes and beyond

• Published in: Thrombosis and haemostasis Vol. 116; no. 2; p. 220
• Main Authors: Santilli, Francesca, Marchisio, Marco, Lanuti, Paola, Boccatonda, Andrea, Miscia, Sebastiano, Davì, Giovanni
• Format: Journal Article
• Language: English
• Published: Germany 01.08.2016
• Subjects: Acute Coronary Syndrome - blood; Acute Coronary Syndrome - etiology; Atherosclerosis - blood; Atherosclerosis - etiology; Biomarkers - blood; Blood Platelets - pathology; Cardiovascular Diseases - blood; Cardiovascular Diseases - etiology; Cell-Derived Microparticles - pathology; Diabetes Mellitus - blood; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetic Cardiomyopathies - blood; Diabetic Cardiomyopathies - etiology; Endothelial Cells - pathology; Humans; Plaque, Atherosclerotic - blood; Plaque, Atherosclerotic - etiology; Risk Factors; Stroke - blood; Stroke - etiology; Thromboplastin - metabolism; atherosclerosis; platelet; tissue factor; diabetes; Microparticles

The term microparticle (MP) identifies a heterogeneous population of vesicles playing a relevant role in the pathogenesis of vascular diseases, cancer and metabolic diseases such as diabetes mellitus. MPs are released by virtually all cell types by shedding during cell growth, proliferation, activat...