Exploring the limits of single emitter detection in fluorescence and extinction

We present an experimental comparison and a theoretical analysis of the signal-to-noise ratios in fluorescence and extinction spectroscopy of a single emitter. We show that because of its homodyne nature the extinction measurements can be advantageous if the emitter is weakly excited. Furthermore, w...

Full description

Saved in:
Bibliographic Details
Published inOptics express Vol. 16; no. 22; pp. 17358 - 17365
Main Authors Wrigge, G, Hwang, J, Gehardt, I, Zumofen, G, Sandoghdar, V
Format Journal Article
LanguageEnglish
Published United States 27.10.2008
Online AccessGet full text

Cover

Loading…
Abstract We present an experimental comparison and a theoretical analysis of the signal-to-noise ratios in fluorescence and extinction spectroscopy of a single emitter. We show that because of its homodyne nature the extinction measurements can be advantageous if the emitter is weakly excited. Furthermore, we discuss the potential of this method for the detection and spectroscopy of weakly emitting systems such as rare earth ions.
AbstractList We present an experimental comparison and a theoretical analysis of the signal-to-noise ratios in fluorescence and extinction spectroscopy of a single emitter. We show that because of its homodyne nature the extinction measurements can be advantageous if the emitter is weakly excited. Furthermore, we discuss the potential of this method for the detection and spectroscopy of weakly emitting systems such as rare earth ions.
Author Gehardt, I
Sandoghdar, V
Zumofen, G
Hwang, J
Wrigge, G
Author_xml – sequence: 1
  givenname: G
  surname: Wrigge
  fullname: Wrigge, G
  organization: Laboratory of Physical Chemistry and opt ETH, ETH Zürich, Zürich, Switzerland
– sequence: 2
  givenname: J
  surname: Hwang
  fullname: Hwang, J
– sequence: 3
  givenname: I
  surname: Gehardt
  fullname: Gehardt, I
– sequence: 4
  givenname: G
  surname: Zumofen
  fullname: Zumofen, G
– sequence: 5
  givenname: V
  surname: Sandoghdar
  fullname: Sandoghdar, V
BackLink https://www.ncbi.nlm.nih.gov/pubmed/18958019$$D View this record in MEDLINE/PubMed
BookMark eNpNkL1PwzAQxS1URGlhY0aemEixY8d2RlSFD6lSFpgtNzmDUWKX2JHKf0-glWC6d3c_PT29BZr54AGhK0pWlAl-V1crKlaESlaoE3ROSckzTpSc_dNztIjxgxDKZSnP0JyqslCElueorva7LgzOv-H0DrhzvUsRB4vjdOoAw7QnGHALCZrkgsfOY9uNYYDYgG8AG99i2Cfnf98X6NSaLsLlcS7R60P1sn7KNvXj8_p-kzUslylTUhhKcsVZwSkXinGat400tilsISZm2yrBLBAjJ9ESRq1g1PBSKaZsa9kS3Rx8d0P4HCEm3bspUNcZD2GMWpQyLwolJ_D2ADZDiHEAq3eD683wpSnRPwXqutJU6EOBE3599B23PbR_8LEx9g0CtWzo
CitedBy_id crossref_primary_10_1103_PhysRevLett_108_093601
crossref_primary_10_1103_PhysRevA_95_053831
crossref_primary_10_1038_nphoton_2010_290
crossref_primary_10_1021_ac901410w
crossref_primary_10_1088_2058_9565_ab3d56
crossref_primary_10_1126_science_1195475
crossref_primary_10_1021_acs_nanolett_9b01822
crossref_primary_10_1038_nphoton_2016_63
crossref_primary_10_2971_jeos_2009_09014
Cites_doi 10.1073/pnas.97.3.996
10.1038/nphys812
10.1103/PhysRevLett.93.037401
10.1103/PhysRevLett.65.2716
10.1016/0009-2614(90)85485-U
10.1103/PhysRevLett.96.013901
10.1021/nl070766y
10.1103/PhysRevLett.93.127401
10.1126/science.7973650
10.1146/annurev.physchem.54.011002.103816
10.1364/OL.8.000177
10.1126/science.265.5168.46
10.1126/science.262.5138.1422
10.1063/1.1609243
10.1364/OL.32.001420
10.1021/nl0717255
10.1103/PhysRevLett.87.183602
10.1364/OL.28.001686
10.1103/PhysRevLett.98.033601
10.1016/S0022-2313(02)00252-1
10.1103/PhysRevLett.62.2535
10.1063/1.1323553
10.1364/OPEX.14.000405
ContentType Journal Article
DBID NPM
AAYXX
CITATION
7X8
DOI 10.1364/OE.16.017358
DatabaseName PubMed
CrossRef
MEDLINE - Academic
DatabaseTitle PubMed
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Physics
EISSN 1094-4087
EndPage 17365
ExternalDocumentID 10_1364_OE_16_017358
18958019
Genre Journal Article
GroupedDBID ---
123
29N
2WC
8SL
AAWJZ
ACGFO
ADBBV
AENEX
AKGWG
ALMA_UNASSIGNED_HOLDINGS
ATHME
AYPRP
AZSQR
AZYMN
BAWUL
BCNDV
C1A
CS3
DIK
DSZJF
DU5
E3Z
EBS
EJD
F5P
GROUPED_DOAJ
GX1
KQ8
M~E
NPM
OFLFD
OK1
OPJBK
OPLUZ
P2P
RNS
ROP
ROS
TR2
TR6
XSB
AAYXX
CITATION
7X8
ID FETCH-LOGICAL-c327t-876a1028435414683412dc7afc5f56c32bd863fe0a7d86d031f631a498838fdf3
ISSN 1094-4087
IngestDate Thu Apr 11 19:22:27 EDT 2024
Wed Jul 24 12:28:45 EDT 2024
Thu May 23 23:55:23 EDT 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 22
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c327t-876a1028435414683412dc7afc5f56c32bd863fe0a7d86d031f631a498838fdf3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
OpenAccessLink https://doi.org/10.1364/oe.16.017358
PMID 18958019
PQID 69725587
PQPubID 23479
PageCount 8
ParticipantIDs proquest_miscellaneous_69725587
crossref_primary_10_1364_OE_16_017358
pubmed_primary_18958019
PublicationCentury 2000
PublicationDate 2008-Oct-27
2008-10-27
20081027
PublicationDateYYYYMMDD 2008-10-27
PublicationDate_xml – month: 10
  year: 2008
  text: 2008-Oct-27
  day: 27
PublicationDecade 2000
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Optics express
PublicationTitleAlternate Opt Express
PublicationYear 2008
References Plakhotnik (oe-16-22-17358-R7) 2001; 87
Lindfors (oe-16-22-17358-R17) 2004; 93
Vamivakas (oe-16-22-17358-R15) 2007; 7
Schultz (oe-16-22-17358-R22) 2000; 97
Plakhotnik (oe-16-22-17358-R14) 2002; 98
Ewers (oe-16-22-17358-R21) 2007; 7
Sonnichsen (oe-16-22-17358-R23) 2000; 77
Moerner (oe-16-22-17358-R13) 1994; 265
Alen (oe-16-22-17358-R8) 2003; 83
Moerner (oe-16-22-17358-R2) 1989; 62
Gerhardt (oe-16-22-17358-R10) 2007; 32
Betzig (oe-16-22-17358-R5) 1993; 262
Gerhardt (oe-16-22-17358-R9) 2007; 98
Jacobsen (oe-16-22-17358-R19) 2006; 14
Mikhailovsky (oe-16-22-17358-R16) 2003; 28
Yuen (oe-16-22-17358-R12) 1983; 8
Nie (oe-16-22-17358-R6) 1994; 266
Arbouet (oe-16-22-17358-R18) 2004; 93
Ignatovich (oe-16-22-17358-R20) 2006; 96
Orrit (oe-16-22-17358-R3) 1990; 65
Shera (oe-16-22-17358-R4) 1990; 174
Wrigge (oe-16-22-17358-R11) 2008; 4
Kulzer (oe-16-22-17358-R1) 2004; 55
References_xml – volume: 97
  start-page: 996
  year: 2000
  ident: oe-16-22-17358-R22
  publication-title: PNAS
  doi: 10.1073/pnas.97.3.996
  contributor:
    fullname: Schultz
– volume: 4
  start-page: 60
  year: 2008
  ident: oe-16-22-17358-R11
  publication-title: Nature Phys.
  doi: 10.1038/nphys812
  contributor:
    fullname: Wrigge
– volume: 93
  start-page: 037401
  year: 2004
  ident: oe-16-22-17358-R17
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.93.037401
  contributor:
    fullname: Lindfors
– volume: 65
  start-page: 2716
  year: 1990
  ident: oe-16-22-17358-R3
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.65.2716
  contributor:
    fullname: Orrit
– volume: 174
  start-page: 553
  year: 1990
  ident: oe-16-22-17358-R4
  publication-title: Chem. Phys. Lett.
  doi: 10.1016/0009-2614(90)85485-U
  contributor:
    fullname: Shera
– volume: 96
  start-page: 013901
  year: 2006
  ident: oe-16-22-17358-R20
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.96.013901
  contributor:
    fullname: Ignatovich
– volume: 7
  start-page: 2263
  year: 2007
  ident: oe-16-22-17358-R21
  publication-title: Nano Lett.
  doi: 10.1021/nl070766y
  contributor:
    fullname: Ewers
– volume: 93
  start-page: 127401
  year: 2004
  ident: oe-16-22-17358-R18
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.93.127401
  contributor:
    fullname: Arbouet
– volume: 266
  start-page: 1018
  year: 1994
  ident: oe-16-22-17358-R6
  publication-title: Science
  doi: 10.1126/science.7973650
  contributor:
    fullname: Nie
– volume: 55
  start-page: 585
  year: 2004
  ident: oe-16-22-17358-R1
  publication-title: Annu. Rev. Phys. Chem.
  doi: 10.1146/annurev.physchem.54.011002.103816
  contributor:
    fullname: Kulzer
– volume: 8
  start-page: 177
  year: 1983
  ident: oe-16-22-17358-R12
  publication-title: Opt. Lett.
  doi: 10.1364/OL.8.000177
  contributor:
    fullname: Yuen
– volume: 265
  start-page: 46
  year: 1994
  ident: oe-16-22-17358-R13
  publication-title: Science
  doi: 10.1126/science.265.5168.46
  contributor:
    fullname: Moerner
– volume: 262
  start-page: 1422
  year: 1993
  ident: oe-16-22-17358-R5
  publication-title: Science
  doi: 10.1126/science.262.5138.1422
  contributor:
    fullname: Betzig
– volume: 83
  start-page: 2235
  year: 2003
  ident: oe-16-22-17358-R8
  publication-title: Appl. Phys. Lett.
  doi: 10.1063/1.1609243
  contributor:
    fullname: Alen
– volume: 32
  start-page: 1420
  year: 2007
  ident: oe-16-22-17358-R10
  publication-title: Opt. Lett.
  doi: 10.1364/OL.32.001420
  contributor:
    fullname: Gerhardt
– volume: 7
  start-page: 2892
  year: 2007
  ident: oe-16-22-17358-R15
  publication-title: Nano Lett.
  doi: 10.1021/nl0717255
  contributor:
    fullname: Vamivakas
– volume: 87
  start-page: 183602
  year: 2001
  ident: oe-16-22-17358-R7
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.87.183602
  contributor:
    fullname: Plakhotnik
– volume: 28
  start-page: 1686
  year: 2003
  ident: oe-16-22-17358-R16
  publication-title: Opt. Lett.
  doi: 10.1364/OL.28.001686
  contributor:
    fullname: Mikhailovsky
– volume: 98
  start-page: 033601
  year: 2007
  ident: oe-16-22-17358-R9
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.98.033601
  contributor:
    fullname: Gerhardt
– volume: 98
  start-page: 57
  year: 2002
  ident: oe-16-22-17358-R14
  publication-title: J. Lumin.
  doi: 10.1016/S0022-2313(02)00252-1
  contributor:
    fullname: Plakhotnik
– volume: 62
  start-page: 2535
  year: 1989
  ident: oe-16-22-17358-R2
  publication-title: Phys. Rev. Lett.
  doi: 10.1103/PhysRevLett.62.2535
  contributor:
    fullname: Moerner
– volume: 77
  start-page: 2949
  year: 2000
  ident: oe-16-22-17358-R23
  publication-title: Appl. Phys. Lett.
  doi: 10.1063/1.1323553
  contributor:
    fullname: Sonnichsen
– volume: 14
  start-page: 405
  year: 2006
  ident: oe-16-22-17358-R19
  publication-title: Opt. Express
  doi: 10.1364/OPEX.14.000405
  contributor:
    fullname: Jacobsen
SSID ssj0014797
Score 2.053241
Snippet We present an experimental comparison and a theoretical analysis of the signal-to-noise ratios in fluorescence and extinction spectroscopy of a single emitter....
SourceID proquest
crossref
pubmed
SourceType Aggregation Database
Index Database
StartPage 17358
Title Exploring the limits of single emitter detection in fluorescence and extinction
URI https://www.ncbi.nlm.nih.gov/pubmed/18958019
https://search.proquest.com/docview/69725587
Volume 16
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEBZNSqGXkkcf2yQbHdpT8XZty5J9DGGbdCHdSwKhFyPrAYGtvSReGnLob8_oYXmTbiHNxciDZRvNx2hGmm-E0CcpObX0M1kIHpFKyyinmkeCwnSj07jKxoacfPaDnl6Q6WV22dMVLbukrUbibi2v5DlaBRno1bBk_0Oz4aUggDboF66gYbg-Scd9Ap1xH-eGq2QzM0z8P1dfFNy7E8BbJbqkRj1fNte2hpOnCoB1vqpF0I93VGcLW79Z3S5CjoaP5d1Z7CejAIjffsl5GkQnynC5rHn_HoQ_l78a7Yyc79wtNtjKr4677-0jRIMQcvo5Uq2RdUaVroDHMY-9iYxZ6oq1_2W8U0pgxGeTUUxH4_DYwxrZj-aukFFoN-YoKWeTMqal672BXiasyEyi59mfSdhbIswdudP9tqdDQO-vq99-6Kj8I_qwXsj5Fnrjwwd85LCwjV6oege9smm84mYXzQIiMCACO0TgRmOHCOwRgQMi8FWNVxGBARG4R8RbdPFtcn58GvkjMyKRJqw1cxs3LiM4wcSQ6sBHSaRgXItMZxSeqWROU63GnEFDgkXXNI05KfI8zbXU6Tu0WTe1-oAw4SqRPGc6qTJCVMaZIFQyITWH9lgM0OdufMqFq4xSrtPCAB12g1eC6TL7UbxWzfKmpAWDgDZnA_TejWn_nrzIwHUqPj7xG3vodY_WfbTZXi_VATiLbTW0iyxDi4B7mwZpNw
link.rule.ids 315,786,790,870,27955,27956
linkProvider ISSN International Centre
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Exploring+the+limits+of+single+emitter+detection+in+fluorescence+and+extinction&rft.jtitle=Optics+express&rft.au=Wrigge%2C+G.&rft.au=Hwang%2C+J.&rft.au=Gehardt%2C+I.&rft.au=Zumofen%2C+G.&rft.date=2008-10-27&rft.issn=1094-4087&rft.eissn=1094-4087&rft.volume=16&rft.issue=22&rft.spage=17358&rft_id=info:doi/10.1364%2FOE.16.017358&rft.externalDBID=n%2Fa&rft.externalDocID=10_1364_OE_16_017358
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1094-4087&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1094-4087&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1094-4087&client=summon