Electronic Cigarettes Enhance Replication of Mycobacterium abscessus in Airway Epithelial Cells

• Published in: American journal of respiratory cell and molecular biology Vol. 60; no. 6; pp. 717 - 719
• Main Authors: Korukonda, Anu, Zhang, Chongxu, Rodriguez, Leslie, Guerrero, Andrea, Campos, Michael, Holt, Gregory, Fregien, Nevis L, Conner, Greg, Mirsaeidi, Mehdi
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 01.06.2019
• Subjects: Adolescents; Aged; Alcohol; Animals; Antibiotic resistance; Antibiotics; Bacteria; Cell walls; Chronic obstructive pulmonary disease; Cigarettes; Cytokines; Cytokines - metabolism; Electronic cigarettes; Electronic Nicotine Delivery Systems; Endothelial cells; Epithelial cells; Epithelial Cells - microbiology; Epithelial Cells - pathology; Epithelial Cells - ultrastructure; Gene expression; Glycopeptidolipids; Humans; Infections; Lung - microbiology; Lung - pathology; Lungs; Macrolide antibiotics; Macrophages; Male; Mice; Middle Aged; Mycobacterium abscessus; Mycobacterium abscessus - growth & development; Nicotine; Oxidative stress; Replication; Respiratory tract; Smoking; Teenagers; Transmission electron microscopy; Young adults; Florida; United States > US

[...]of this perception, ECs have become popular among children in middle school and high school (3). Mycobacterium abscessus (MAB) has been found to be the one of the most isolated species of nontuberculous mycobacteria in the southeastern region of the United States (Florida to Texas) (8). Because...