Machine learning-enhanced MALDI-TOF MS for real-time detection of antibiotic-resistant E. coli in food processing

• Published in: Food science & technology Vol. 224; p. 117860
• Main Authors: Victor Lin, Hong-Ting, Yang, Tien-Wei, Lu, Wen-Jung, Chiang, Hong-Jhen, Hsu, Pang-Hung
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 15.05.2025
• Subjects: algorithms; antibiotic resistance; Antimicrobial resistance; carbapenems; chloramphenicol; desorption; Escherichia coli; food production; Food safety; Machine learning; MALDI-TOF MS; mass spectrometry; monitoring; penicillins; prediction; public health; quinolones; Rapid detection; rapid methods; risk; streptomycin; tetracycline; MALDI-TOF MS; Food safety; Antimicrobial resistance; Rapid detection; Machine learning

Antibiotic-resistant Escherichia coli in food processing poses a significant risk to public health, necessitating rapid detection methods. This study developed an innovative approach combining matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) with machine le...