MR angiography with gadofosveset trisodium for peripheral vascular disease: phase II trial

• Published in: Radiology Vol. 229; no. 3; p. 811
• Main Authors: Perreault, Pierre, Edelman, Mark A, Baum, Richard A, Yucel, E Kent, Weisskoff, Robert M, Shamsi, Kohkan, Mohler, 3rd, Emile R
• Format: Journal Article
• Language: English
• Published: United States 01.12.2003
• Subjects: Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gadolinium; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Organometallic Compounds - adverse effects; Peripheral Vascular Diseases - diagnosis; Peripheral Vascular Diseases - diagnostic imaging; ROC Curve; Safety

To evaluate the dose response and safety of gadofosveset trisodium-enhanced magnetic resonance (MR) angiography compared with nonenhanced two-dimensional time-of-flight MR angiography and with x-ray angiography as the standard. In this randomized, 20-center, double-blind study, 238 men and women who...