Can inflammation relieve pain?

Immune cells secreting the opioid peptide beta -endorphin undergo selectin- mediated migration to peripheral sites of injury where they promote analgesia.

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Bibliographic Details
Published inNature medicine Vol. 4; no. 12; pp. 1359 - 1360
Main Authors Porreca, Frank, Lai, Josephine, Malan, T. Philip
Format Journal Article
LanguageEnglish
Published United States 01.12.1998
Subjects
Analgesia
Animals
beta-Endorphin - secretion
Cell Movement
Drug Design
Humans
Immune System - cytology
Immune System - immunology
Immune System - physiology
Inflammation - immunology
Inflammation - pathology
Nociceptors - physiology
Pain - immunology
Pain - pathology
Selectins - physiology
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Summary:Immune cells secreting the opioid peptide beta -endorphin undergo selectin- mediated migration to peripheral sites of injury where they promote analgesia.
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ISSN:1078-8956
1546-170X
DOI:10.1038/3942