Toxicological evaluations of combined administration of ethanolic stem bark extract of Enantia chlorantha and lisinopril in experimental type 2 diabetes

• Published in: Clinical phytoscience Vol. 6; no. 1; pp. 1 - 9
• Main Authors: Ajani, Emmanuel Oladipo, Ibrahim, Latifat Bolanle
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 23.05.2020; Springer Nature B.V; SpringerOpen
• Subjects: Acute toxicity; Antihypertensives; Bark; Bilirubin; Biomarkers; Cholestasis; Creatinine; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Drug-herb interaction; Ethanol; Fatty liver; Fructose; Gastroenterology; Gynecology; Hematology; Herbal medicine; Kidneys; Liver; Liver diseases; Liver function; Maceration; Medicinal plants; Medicine; Medicine & Public Health; Oral administration; Original Contribution; Pediatrics; Pharmacodynamics; Plant extracts; Pneumology/Respiratory System; Restoration; Rodents; Stems; Streptozocin; Synergistic effect; Toxicity; Urea; Liver function; Pharmacodynamics; Drug-herb interaction; Diabetes; Toxicity

Background Enantia chlorantha is a local medicinal plant commonly use in Nigeria for the treatment of diabetes but without support of scientific data. Large percentage of people suffering from diabetes who uses the plant as antidiabetic agent also combine its administration with standard antihyperte...