CPLX2 is a novel tumor suppressor and improves the prognosis in glioma

• Published in: Journal of neuro-oncology Vol. 167; no. 1; pp. 63 - 74
• Main Authors: Chen, Yuanbing, Ning, Jieling, Shu, Long, Wen, Lingzhi, Yan, Bokang, Wang, Zuli, Hu, Junhong, Zhou, Xiaokun, Tao, Yongguang, Xia, Xuewei, Huang, Jun
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2024; Springer Nature B.V
• Subjects: Cell proliferation; Central nervous system; Genomes; Glioma; Glioma cells; Hypoxia; Malignancy; Medical prognosis; Medicine; Medicine & Public Health; Molecular modelling; Neurology; Oncology; Prognosis; Transcriptomes; Tumor suppression; Tumor suppressor genes; Tumorigenesis; Hypoxia; Inflammation; Glioma; CPLX2; Tumor suppressor gene

Background Glioma is a type of malignant cancer that affect the central nervous system. New predictive biomarkers have been investigated in recent years, but the clinical prognosis for glioma remains poor. The function of CPLX2 in glioma and the probable molecular mechanism of tumor suppression were...