Septin genomics: a road less travelled

• Published in: Biological chemistry Vol. 392; no. 8-9; pp. 763 - 767
• Main Authors: Russell, S.E. Hilary, Hall, Peter A.
• Format: Journal Article
• Language: English
• Published: Germany Walter de Gruyter 01.08.2011
• Subjects: Cell Cycle Proteins - classification; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; gene family; Genomics - methods; Humans; nonsense mediated decay; Nonsense Mediated mRNA Decay - genetics; Nonsense Mediated mRNA Decay - physiology; Protein Isoforms - classification; Protein Isoforms - genetics; Protein Isoforms - metabolism; pseudogene; regulation; septin; Septins - classification; Septins - genetics; Septins - metabolism

The human septins are part of a gene family, that is a group of genes with similar sequences and usually but not invariably share similar functions that are descended from a common ancestor. Here we review our current knowledge of the human septin gene family and highlight areas of uncertainty. Curr...