TEAM: A MULTIPLE TESTING ALGORITHM ON THE AGGREGATION TREE FOR FLOW CYTOMETRY ANALYSIS

• Published in: The annals of applied statistics Vol. 17; no. 1; p. 621
• Main Authors: Pura, John A, Li, Xuechan, Chan, Cliburn, Xie, Jichun
• Format: Journal Article
• Language: English
• Published: United States 01.03.2023
• Subjects: Flow cytometry; aggregation tree; distribution difference; multiple testing; false discovery proportion (FDP)

In immunology studies, flow cytometry is a commonly used multivariate single-cell assay. One key goal in flow cytometry analysis is to detect the immune cells responsive to certain stimuli. Statistically, this problem can be translated into comparing two protein expression probability density functi...