Effects of Statistical Practices for Longitudinal Group Comparison of the Penetration-Aspiration Scale on Power and Effect Size Estimation: A Monte Carlo Simulation Study

• Published in: Dysphagia Vol. 40; no. 2; pp. 388 - 398
• Main Authors: Borders, James C., Grande, Alessandro A., Barbon, Carly E. A., Hutcheson, Katherine A., Troche, Michelle S.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2025; Springer Nature B.V
• Subjects: Clinical outcomes; Clinical trials; Deglutition - physiology; Deglutition Disorders - diagnosis; Deglutition Disorders - etiology; Deglutition Disorders - physiopathology; Estimates; Gastroenterology; Head & neck cancer; Head and Neck Neoplasms - complications; Head and Neck Neoplasms - physiopathology; Hepatology; Humans; Imaging; Longitudinal Studies; Medicine; Medicine & Public Health; Models, Statistical; Monte Carlo Method; Monte Carlo simulation; Movement disorders; Neurodegenerative diseases; Original Article; Otorhinolaryngology; Parkinson Disease - complications; Parkinson Disease - physiopathology; Parkinson's disease; Radiology; Respiratory Aspiration - diagnosis; Respiratory Aspiration - etiology; Respiratory Aspiration - physiopathology; Severity of Illness Index; Statistical analysis; Statistical models; Statistical power; Swallowing; Dysphagia; Meta-science; Deglutition disorders; Statistics; Multilevel models

Multiple bolus trials are administered during clinical and research swallowing assessments to comprehensively capture an individual’s swallowing function. Despite valuable information obtained from these boluses, it remains common practice to use a single bolus (e.g., the worst score) to describe th...