AAA+ proteases and their role in distinct stages along the Vibrio cholerae lifecycle

• Published in: International journal of medical microbiology Vol. 306; no. 6; pp. 452 - 462
• Main Authors: Pressler, Katharina, Vorkapic, Dina, Lichtenegger, Sabine, Malli, Gerald, Barilich, Benjamin P, Cakar, Fatih, Zingl, Franz G, Reidl, Joachim, Schild, Stefan
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.09.2016
• Subjects: Animals; Biofilm; Biofilms - growth & development; Cholera; Cholera Toxin - metabolism; Endopeptidase Clp - metabolism; Flagella; Humans; Infectious Disease; Intestinal Mucosa - microbiology; Locomotion; Medical Education; Mice; Motility; Mucosal penetration; Peptide Hydrolases - metabolism; Protein Interaction Maps; Vibrio cholerae - enzymology; Vibrio cholerae - growth & development; Vibrio cholerae - metabolism; Vibrio cholerae - physiology; Virulence; Biofilm; Cholera; Motility; Flagella; Mucosal penetration; Virulence

Abstract The facultative human pathogen Vibrio cholerae has to adapt to different environmental conditions along its lifecycle by means of transcriptional, translational and post-translational regulation. This study provides a first comprehensive analysis regarding the contribution of the cytoplasmi...