Janus Kinase Inhibitor Brepocitinib Rescues Myelin Phagocytosis Under Inflammatory Conditions: In Vitro Evidence from Microglia and Macrophage Cell Lines
Central nervous system (CNS) injuries induce cell death and consequently the release of myelin and other cellular debris. Microglia as well as hematogenous macrophages actively collaborate to phagocyte them and undergo their degradation. However, myelin accumulation persists in the lesion site long...
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Published in | Molecular neurobiology Vol. 61; no. 9; pp. 6423 - 6434 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.09.2024
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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