Thirty-Five Years of Thyroid Cancer Experience in a Paediatric Population: Incidence Trends in Lithuania between 1980 and 2014
Background: Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. Aims: The objectives of this study were to analyse the prevalence and incidence trends over 3 decades and clinical features of TC in the paediatric populat...
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Published in | European thyroid journal Vol. 6; no. 1; pp. 40 - 46 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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S. Karger AG
01.01.2017
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Abstract | Background: Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. Aims: The objectives of this study were to analyse the prevalence and incidence trends over 3 decades and clinical features of TC in the paediatric population in Lithuania. Methods: We reviewed all TC cases diagnosed in children aged less than 18 years during the period 1980-2014 using medical records from 3 main hospitals in Lithuania where such TC cases are managed. Results: During the 35-year period (1980-2014) there were 57 cases (45 females) of TC in children in Lithuania. The mean age at the time of diagnosis was 14.51 ± 0.52 years. The crude incidence rate of TC ranged from 0 to 0.93 cases per 100,000 children per year and the mean annual increase was 5.26% (p < 0.001). Papillary carcinoma was the most common histological type (73.7%). No association was found between the incidence of TC and the reported areas of radioactive contamination after the Chernobyl accident. In total, 8.8% of patients had secondary TC after initial radiotherapy of a primary oncologic disease. Conclusion: The incidence of TC in the Lithuanian paediatric population between 1980 and 2014 ranged from 0 to 0.93 cases per 100,000 children per year and there was a 5.26% annual increase (p < 0.001), most probably related to the increased use of ultrasound testing. |
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AbstractList | Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance.
The objectives of this study were to analyse the prevalence and incidence trends over 3 decades and clinical features of TC in the paediatric population in Lithuania.
We reviewed all TC cases diagnosed in children aged less than 18 years during the period 1980-2014 using medical records from 3 main hospitals in Lithuania where such TC cases are managed.
During the 35-year period (1980-2014) there were 57 cases (45 females) of TC in children in Lithuania. The mean age at the time of diagnosis was 14.51 ± 0.52 years. The crude incidence rate of TC ranged from 0 to 0.93 cases per 100,000 children per year and the mean annual increase was 5.26% (p < 0.001). Papillary carcinoma was the most common histological type (73.7%). No association was found between the incidence of TC and the reported areas of radioactive contamination after the Chernobyl accident. In total, 8.8% of patients had secondary TC after initial radiotherapy of a primary oncologic disease.
The incidence of TC in the Lithuanian paediatric population between 1980 and 2014 ranged from 0 to 0.93 cases per 100,000 children per year and there was a 5.26% annual increase (p < 0.001), most probably related to the increased use of ultrasound testing. BACKGROUNDThyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. AIMSThe objectives of this study were to analyse the prevalence and incidence trends over 3 decades and clinical features of TC in the paediatric population in Lithuania. METHODSWe reviewed all TC cases diagnosed in children aged less than 18 years during the period 1980-2014 using medical records from 3 main hospitals in Lithuania where such TC cases are managed. RESULTSDuring the 35-year period (1980-2014) there were 57 cases (45 females) of TC in children in Lithuania. The mean age at the time of diagnosis was 14.51 ± 0.52 years. The crude incidence rate of TC ranged from 0 to 0.93 cases per 100,000 children per year and the mean annual increase was 5.26% (p < 0.001). Papillary carcinoma was the most common histological type (73.7%). No association was found between the incidence of TC and the reported areas of radioactive contamination after the Chernobyl accident. In total, 8.8% of patients had secondary TC after initial radiotherapy of a primary oncologic disease. CONCLUSIONThe incidence of TC in the Lithuanian paediatric population between 1980 and 2014 ranged from 0 to 0.93 cases per 100,000 children per year and there was a 5.26% annual increase (p < 0.001), most probably related to the increased use of ultrasound testing. Background: Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. Aims: The objectives of this study were to analyse the prevalence and incidence trends over 3 decades and clinical features of TC in the paediatric population in Lithuania. Methods: We reviewed all TC cases diagnosed in children aged less than 18 years during the period 1980-2014 using medical records from 3 main hospitals in Lithuania where such TC cases are managed. Results: During the 35-year period (1980-2014) there were 57 cases (45 females) of TC in children in Lithuania. The mean age at the time of diagnosis was 14.51 ± 0.52 years. The crude incidence rate of TC ranged from 0 to 0.93 cases per 100,000 children per year and the mean annual increase was 5.26% (p < 0.001). Papillary carcinoma was the most common histological type (73.7%). No association was found between the incidence of TC and the reported areas of radioactive contamination after the Chernobyl accident. In total, 8.8% of patients had secondary TC after initial radiotherapy of a primary oncologic disease. Conclusion: The incidence of TC in the Lithuanian paediatric population between 1980 and 2014 ranged from 0 to 0.93 cases per 100,000 children per year and there was a 5.26% annual increase (p < 0.001), most probably related to the increased use of ultrasound testing. |
Author | Verkauskienė, Rasa Poškienė, Lina Kuprionis, Gintaras Jašinskienė, Edita Šemetaitė, Agnė Šidlauskas, Vygantas Makštienė, Jurgita Kiudelienė, Rosita Marčiulionytė, Dalia Bėrontienė, Rima Valickas, Raimondas Žalinkevičius, Rimantas Macaitytė, Raminta |
AuthorAffiliation | a Clinic of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania d Clinic of Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania e Clinic of Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania c Clinic of Radiology, Lithuanian University of Health Sciences, Kaunas, Lithuania f Clinics of Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania b Clinic of Pediatrics, Lithuanian University of Health Sciences, Kaunas, Lithuania |
AuthorAffiliation_xml | – name: a Clinic of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania – name: c Clinic of Radiology, Lithuanian University of Health Sciences, Kaunas, Lithuania – name: f Clinics of Institute of Endocrinology, Lithuanian University of Health Sciences, Kaunas, Lithuania – name: d Clinic of Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania – name: b Clinic of Pediatrics, Lithuanian University of Health Sciences, Kaunas, Lithuania – name: e Clinic of Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania |
Author_xml | – sequence: 1 givenname: Rima surname: Bėrontienė fullname: Bėrontienė, Rima email: rberonti@gmail.com – sequence: 2 givenname: Edita surname: Jašinskienė fullname: Jašinskienė, Edita – sequence: 3 givenname: Rosita surname: Kiudelienė fullname: Kiudelienė, Rosita – sequence: 4 givenname: Gintaras surname: Kuprionis fullname: Kuprionis, Gintaras – sequence: 5 givenname: Jurgita surname: Makštienė fullname: Makštienė, Jurgita – sequence: 6 givenname: Raminta surname: Macaitytė fullname: Macaitytė, Raminta – sequence: 7 givenname: Dalia surname: Marčiulionytė fullname: Marčiulionytė, Dalia – sequence: 8 givenname: Lina surname: Poškienė fullname: Poškienė, Lina – sequence: 9 givenname: Agnė surname: Šemetaitė fullname: Šemetaitė, Agnė – sequence: 10 givenname: Vygantas surname: Šidlauskas fullname: Šidlauskas, Vygantas – sequence: 11 givenname: Raimondas surname: Valickas fullname: Valickas, Raimondas – sequence: 12 givenname: Rimantas surname: Žalinkevičius fullname: Žalinkevičius, Rimantas – sequence: 13 givenname: Rasa surname: Verkauskienė fullname: Verkauskienė, Rasa |
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Copyright | 2016 European Thyroid Association Published by S. Karger AG, Basel Copyright © 2016 by European Thyroid Association Published by S. Karger AG, Basel 2016 |
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Keywords | Thyroid cancer Children Secondary cancer Paediatrics Chernobyl accident Radiation |
Language | English |
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References | Schlumberger M, Pacini F: The Chernobyl accident; in Schlumberger M, Pacini F (eds): Thyroid Tumors. Paris, Nucleon, 1999, pp 239-243. Bėrontienė R: Structural and Functional Changes Caused by Iodine Deficiency in the Thyroid Gland of Lithuanian Children; dissertation, Kaunas, 2002. Niedziela M, Korman E, Breborowicz D, Trejster E, Harasymczuk J, Warzywoda M, Rolski M, Breborowicz J: A prospective study of thyroid nodular disease in children and adolescents in western Poland from 1996 to 2000 and the incidence of thyroid carcinoma relative to iodine deficiency and the Chernobyl disaster. Pediatr Blood Cancer 2004;42:84-92. Brito JP, Hay ID, Morris JC: Low risk papillary thyroid cancer. BMJ 2014;348:g3045. Auvinen A, Seppä K, Pasanen K, Kurttio P, Patama T, Pukkala E, Heinävaara S, Arvela H, Verkasalo P, Hakulinen T: Chernobyl fallout and cancer incidence in Finland 1988-2007. Int J Cancer 2013;134:2253-2263. Zablotska LB, Ron E, Rozhko V, Hatch M, Polyanskaya ON, Brenner AV, Lubin J, Romanov GN, McConnell RJ, O'Kane P, Evseenko VV, Drozdovitch VV, Luckyanov N, Minenko VF, Bouville A, Masyakin VB: Thyroid cancer risk in Belarus among children and adolescents exposed to radioiodine after the Chornobyl accident. Br J Cancer 2011;104:181-187. Shakhtarin VV, Tsyb AF, Stepanenko VF, Orlov MY, Kopecky KJ, Davis S: Iodine deficiency, radiation dose, and the risk of thyroid cancer among children and adolescents in the Bryansk region of Russia following the Chernobyl power station accident. Int J Epidemiol 2003;32:584-591. Catelinois O, Laurier D, Verger P, Rogel A, Colonna M, Ignasiak M, Hémon D, Tirmarche M: Uncertainty and sensitivity analysis in assessment of the thyroid cancer risk related to Chernobyl fallout in Eastern France. Risk Anal 2005;25:243-252. Taylor AJ, Croft AP, Palace AM, Winter DL, Reulen RC, Stiller C, Stevens MC, Hawkins MM: Risk of thyroid cancer in survivors of childhood cancer: results from the British Childhood Cancer Survivor Study. Int J Cancer 2009;125:2400-2405. Reulen RC, Frobisher C, Winter DL, Kelly J, Lancashire ER, Stiller CA, Pritchard-Jones K, Jenkinson HC, Hawkins MM: Long-term risks of subsequent primary neoplasms among survivors of childhood cancer. JAMA 2011;305:2311-2319. American Cancer Society Network: Cancer facts & figures 2012. http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2012 (accessed September 23, 2014). Cardis E, Kesminiene A, Ivanov V, Malakhova I, Shibata Y, Khrouch V, et al: Risk of thyroid cancer after exposure to 131I in childhood. J Natl Cancer Inst 2005;97:724-732. Zimmerman D, Hay ID, Gough IR, Goellner JR, Ryan JJ, Grant CS, McConahey WM: Papillary thyroid carcinoma in children and adults: long-term follow-up of 1,039 patients conservatively treated at one institution during three decades. Surgery 1988;104:1157-1166. Veiga LH, Bhatti P, Ronckers CM, Sigurdson AJ, Stovall M, Smith SA, Weathers R, Leisenring W, Mertens AC, Neglia JP, Meadows AT, Donaldson SS: Chemotherapy ant thyroid cancer risk: a report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev 2012;21:92-101. Vaisman F, Corbo R, Vaisman M: Thyroid carcinoma in children and adolescents - systematic review of the literature. J Thyroid Res 2011;2011:845362. Park S, Jeong JS, Ryu HR, Lee C-R, Park JH, Kang SW, Jeong JJ, Nam KH, Chung WY, Park CS: Differentiated thyroid carcinoma of children and adolescents: 27-year experience in the Yonsei University Health System. J Korean Med Sci 2013;28:693-699. Neglia JP, Friedman DL, Yasui Y, Mertens AC, Hammond S, Stovall M, Donaldson SS, Meadows AT, Robison LL: Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study. J Natl Cancer Inst 2001;93:618-629. Alessandri AJ, Goddard KJ, Blair GK, Fryer CJ, Schultz KR: Age is the major determinant of recurrence in pediatric differentiated thyroid carcinoma. Med Pediatr Oncol 2000;35:41-46. Pettersson B, Adami HO, Wilander E, Coleman MP: Trends in thyroid cancer incidence in Sweden, 1958-1981, by histopathologic type. Int J Cancer 1991;48:28-33. Cardis E, Howe G, Ron E, Bebeshko V, Bogdanova T, Bouville A, et al: Cancer consequences of the Chernobyl accident: 20 years on. J Radiol Prot 2006;26:127-140. Collini P, Massimino M, Leite SF, Mattavelli F, Seregni E, Zucchini N, Spreafico F, Ferrari A, Castellani MR, Cantù G, Fossati-Bellani F, Rosai J: Papillary thyroid carcinoma of childhood and adolescence: a 30-year experience at the Istituto Nazionale Tumori in Milan. Pediatr Blood Cancer 2006;46:300-306. Tucker MA, Jones PH, Boice JD, Robison LL, Stone BJ, Stovall M, Jenkin RD, Lubin JH, Baum ES, Siegel SE, Meadows AT, Hoover RN, Fraumeni JF: Therapeutic radiation at a young age is linked to secondary thyroid cancer. Cancer Res 1991;51:2885-2888. Nottage K, McFarlane J, Krasin MJ, Li C, Srivastava D, Robison LL, Hudson MM: Secondary colorectal carcinoma after childhood cancer. J Clin Oncol 2012;30:2552-2558. Bhatti P, Veiga LH, Ronckers CM, Sigurdson AJ, Stovall M, Smith SA, Weathers R, Leisenring W, Mertens AC, Hammond S, Friedman DL, Neglia JP, Meadows AT, Donaldson SS, Sklar CA, Robison LL, Inskip PD: Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study. Radiat Res 2010;174:741-752. Brenner AV, Tronko MD, Hatch M, Bogdanova TI, Oliynik V, Lubin JH, Zablotska LB, Tereschenko VP, McConnell RJ, Zamotaeva G, O'Kane P, Bouville AC, Chaykovskaya LV, Greenebaum E, Paster IP, Shpak VM, Ron E: I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. Environ Health Perspect 2011;119:933-939. Ronckers CM, Sigurdson AJ, Stovall M, Smith SA, Mertens AC, Liu Y, Hammond S, Land CE, Neglia JP, Donaldson SS, Meadows AT, Sklar CA, Robison LL, Inskip PD: Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers. Radiat Res 2006;166:618-628. Bleyer A, Viny A, Barr R: Cancer in 15- to 29-year-olds by primary site. Oncologist 2006;11:590-601. Sigurdson AJ, Ronckers CM, Mertens AC, Stovall M, Smith SA, Liu Y, Berkow RL, Hammond S, Neglia JP, Meadows AT, Sklar CA, Robison LL, Inskip PD: Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study): a nested case-control study. Lancet 2005;365:2014-2023. Demidchik YE, Saenko VA, Yamashita S: Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present. Arq Bras Endocrinol Metabol 2007;51:748-762. Nedveckaite T: Radioactive contamination after Chernobyl accident in Lithuania; in Radiation Protection in Lithuania. Vilnius, Kriventa, 2004, pp 103-115. 21102590 - Br J Cancer. 2011 Jan 4;104(1):181-7 22028399 - Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):92-101 3194843 - Surgery. 1988 Dec;104(6):1157-66 21904689 - J Thyroid Res. 2011;2011:845362 15876201 - Risk Anal. 2005 Apr;25(2):243-52 21128798 - Radiat Res. 2010 Dec;174(6):741-52 23678260 - J Korean Med Sci. 2013 May;28(5):693-9 11309438 - J Natl Cancer Inst. 2001 Apr 18;93(8):618-29 12913034 - Int J Epidemiol. 2003 Aug;32(4):584-91 24135935 - Int J Cancer. 2014 May 1;134(9):2253-63 19610069 - Int J Cancer. 2009 Nov 15;125(10 ):2400-5 17891238 - Arq Bras Endocrinol Metabol. 2007 Jul;51(5):748-62 21642683 - JAMA. 2011 Jun 8;305(22):2311-9 16047353 - Pediatr Blood Cancer. 2006 Mar;46(3):300-6 21406336 - Environ Health Perspect. 2011 Jul;119(7):933-9 24935445 - BMJ. 2014 Jun 16;348:g3045 14752799 - Pediatr Blood Cancer. 2004 Jan;42(1):84-92 16794238 - Oncologist. 2006 Jun;11(6):590-601 16738412 - J Radiol Prot. 2006 Jun;26(2):127-40 15950715 - Lancet. 2005 Jun 11-17;365(9476):2014-23 2019455 - Int J Cancer. 1991 Apr 22;48(1):28-33 10881006 - Med Pediatr Oncol. 2000 Jul;35(1):41-6 1851664 - Cancer Res. 1991 Jun 1;51(11):2885-8 15900042 - J Natl Cancer Inst. 2005 May 18;97(10):724-32 22665546 - J Clin Oncol. 2012 Jul 10;30(20):2552-8 17007558 - Radiat Res. 2006 Oct;166(4):618-28 |
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Snippet | Background: Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. Aims: The... Thyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. The objectives of this... BACKGROUNDThyroid cancer (TC) is a rare condition in children. It may be associated with radiation, iodine deficiency or familial inheritance. AIMSThe... |
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Title | Thirty-Five Years of Thyroid Cancer Experience in a Paediatric Population: Incidence Trends in Lithuania between 1980 and 2014 |
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