Advances in ion beam micromachining for complex 3D microfluidics

In this paper, the authors present microfluidic mixers containing complex curvilinear and several tens of microns deep three-dimensional (3D) geometries used to decrease mixing lengths in passive microfluidic systems. In order to create these 3D geometries, the authors use ion beam micromachining (I...

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Published inJournal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Vol. 31; no. 6; pp. 6 - 12
Main Authors Ocola, Leonidas E., Palacios, Edgar
Format Journal Article
LanguageEnglish
Published 01.11.2013
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Abstract In this paper, the authors present microfluidic mixers containing complex curvilinear and several tens of microns deep three-dimensional (3D) geometries used to decrease mixing lengths in passive microfluidic systems. In order to create these 3D geometries, the authors use ion beam micromachining (IBμM) and address redeposition and exposure strategy effects that follow this type of fabrication. Results of this work clearly demonstrate that fabrication of 3D microfluidic mixers using IBμM is achievable for real practical applications. In order to scale up to the tens of microns width and depth, and hundreds of microns in length fabrication, high current is required. This raises unique challenges of redeposition handling. This was achieved by realizing that redeposited silicon can be removed with an extended buffered oxide etch. In addition, data management and writing strategies not encountered in electron beam lithography have to be considered when designing the solid to be milled. Both designs, straight 3D and serpentine 3D mixers, were significantly faster mixers than the standard focusing mixer with no 3D texturing. This demonstrates that adding programmed depth variations to existing microfluidic devices can open new opportunities in microfluidic research and IBμM.
AbstractList In this paper, the authors present microfluidic mixers containing complex curvilinear and several tens of microns deep three-dimensional (3D) geometries used to decrease mixing lengths in passive microfluidic systems. In order to create these 3D geometries, the authors use ion beam micromachining (IBμM) and address redeposition and exposure strategy effects that follow this type of fabrication. Results of this work clearly demonstrate that fabrication of 3D microfluidic mixers using IBμM is achievable for real practical applications. In order to scale up to the tens of microns width and depth, and hundreds of microns in length fabrication, high current is required. This raises unique challenges of redeposition handling. This was achieved by realizing that redeposited silicon can be removed with an extended buffered oxide etch. In addition, data management and writing strategies not encountered in electron beam lithography have to be considered when designing the solid to be milled. Both designs, straight 3D and serpentine 3D mixers, were significantly faster mixers than the standard focusing mixer with no 3D texturing. This demonstrates that adding programmed depth variations to existing microfluidic devices can open new opportunities in microfluidic research and IBμM.
Author Palacios, Edgar
Ocola, Leonidas E.
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Cites_doi 10.1103/PhysRevLett.80.3863
10.1088/0960-1317/15/2/R01
10.1088/0022-3727/46/11/114001
10.1088/0022-3727/46/11/114002
10.1116/1.3308974
10.1039/b005319h
10.1116/1.568546
10.1016/0167-9317(86)90009-2
10.1039/c2lc21015k
10.1063/1.90786
10.1109/84.846699
10.1038/215950a0
10.1116/1.1318486
10.1016/j.cirp.2009.09.007
10.1116/1.3505128
10.1088/0957-4484/24/17/175302
10.1038/218202a0
10.1007/s10404-009-0456-z
10.1063/1.1663422
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Keywords hydrofluoric acid
Silicon
Polydimethylsiloxane
Fluorescein
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References Drummond, Long (c2) 1967; 215
Toma, Dootz, Pfohl (c14) 2013; 46
Tofteberg, Skolimowski, Andreassen, Geschke (c19) 2010; 8
Hill (c3) 1968; 218
Liu, Stremler, Sharp, Olsen, Santiago, Adrian (c17) 2000; 9
Seliger, Fleming (c4) 1973; 10
Liao (c13) 2012; 12
Imre, Ocola, Rich, Klingfus (c9) 2010; 28
Holz, Heil, Sacco (c20) 2000; 2
Knight, Vishwanath, Brody, Austin (c16) 1998; 80
Palacios, Ocola, Joshi-Imre, Bauerdick, Berse, Peto (c10) 2010; 28
Nunes, Tsai, Wan, Stone (c15) 2013; 46
Seliger, Fleming (c5) 1974; 45
Kanaya, Kawakatsu, Matsui, Yamazaki (c1) 1964; 21
Seliger, Ward (c6) 1975; 12
Allen, Shore, Evans, Fanara, O'Brien, Marson, O'Neill (c11) 2009; 58
Wu (c8) 2013; 24
Seliger, Ward, Wang, Kubena (c7) 1979; 34
Morimoto, Sasaki, Saitoh, Tatakabe, Kato (c12) 1986; 4
Nguyen, Wu (c18) 2005; 15
Kanaya K. (c1) 1964; 21
c20
c11
c10
c13
c12
c15
c14
c17
c16
c19
c18
c2
c3
c4
c5
c6
c7
c8
c9
Nguyen N.-T. (c21) 2002
References_xml – volume: 215
  start-page: 950
  year: 1967
  ident: c2
  publication-title: Nature
– volume: 28
  start-page: 304
  year: 2010
  ident: c9
  publication-title: J. Vac. Sci. Technol. B
– volume: 12
  start-page: 746
  year: 2012
  ident: c13
  publication-title: Lab Chip
– volume: 9
  start-page: 190
  year: 2000
  ident: c17
  publication-title: J. Microelectromech. Syst.
– volume: 34
  start-page: 310
  year: 1979
  ident: c7
  publication-title: Appl. Phys. Lett.
– volume: 21
  start-page: 399
  year: 1964
  ident: c1
  publication-title: Optik
– volume: 2
  start-page: 4740
  year: 2000
  ident: c20
  publication-title: Phys. Chem. Chem. Phys.
– volume: 10
  start-page: 1127
  year: 1973
  ident: c4
  publication-title: J. Vac. Sci. Technol.
– volume: 58
  start-page: 647
  year: 2009
  ident: c11
  publication-title: CIRP Ann.
– volume: 28
  start-page: C6I1
  year: 2010
  ident: c10
  publication-title: J. Vac. Sci. Technol. B
– volume: 24
  start-page: 175302
  year: 2013
  ident: c8
  publication-title: Nanotechnology
– volume: 218
  start-page: 202
  year: 1968
  ident: c3
  publication-title: Nature
– volume: 8
  start-page: 209
  year: 2010
  ident: c19
  publication-title: Microfluid. Nanofluid.
– volume: 80
  start-page: 3863
  year: 1998
  ident: c16
  publication-title: Phys. Rev. Lett.
– volume: 15
  start-page: R1
  year: 2005
  ident: c18
  publication-title: J. Micromech. Microeng.
– volume: 45
  start-page: 1416
  year: 1974
  ident: c5
  publication-title: J. Appl. Phys.
– volume: 12
  start-page: 1378
  year: 1975
  ident: c6
  publication-title: J. Vac. Sci. Technol.
– volume: 46
  start-page: 114002
  year: 2013
  ident: c15
  publication-title: J. Phys. D: Appl. Phys.
– volume: 46
  start-page: 114001
  year: 2013
  ident: c14
  publication-title: J. Phys. D: Appl. Phys.
– volume: 4
  start-page: 163
  year: 1986
  ident: c12
  publication-title: Microelectron. Eng.
– ident: c16
  doi: 10.1103/PhysRevLett.80.3863
– ident: c18
  doi: 10.1088/0960-1317/15/2/R01
– ident: c14
  doi: 10.1088/0022-3727/46/11/114001
– ident: c15
  doi: 10.1088/0022-3727/46/11/114002
– ident: c9
  doi: 10.1116/1.3308974
– ident: c20
  doi: 10.1039/b005319h
– ident: c6
  doi: 10.1116/1.568546
– ident: c12
  doi: 10.1016/0167-9317(86)90009-2
– volume-title: Fundamentals and Applications of Microfluidics
  year: 2002
  ident: c21
– ident: c13
  doi: 10.1039/c2lc21015k
– ident: c7
  doi: 10.1063/1.90786
– volume: 21
  start-page: 399
  year: 1964
  ident: c1
  publication-title: Optik
– ident: c17
  doi: 10.1109/84.846699
– ident: c2
  doi: 10.1038/215950a0
– ident: c4
  doi: 10.1116/1.1318486
– ident: c11
  doi: 10.1016/j.cirp.2009.09.007
– ident: c10
  doi: 10.1116/1.3505128
– ident: c8
  doi: 10.1088/0957-4484/24/17/175302
– ident: c3
  doi: 10.1038/218202a0
– ident: c19
  doi: 10.1007/s10404-009-0456-z
– ident: c5
  doi: 10.1063/1.1663422
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