Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4 + T Cell Proliferation - Celada, Lindsay J.; Rotsinger, Joseph E.; Young, Anjuli; Shaginurova, Guzel; Shelton, Debresha; Hawkins, Charlene; Drake, Wonder P. (American journal of respiratory cell and molecular biology, 2017)
Keywords: Adult; Aged; Case-Control Studies; CD4-Positive T-Lymphocytes - immunology; Cell Proliferation; Demography; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Original Research; Phosphatidylinositol 3-Kinase - metabolism; Programmed Cell Death 1 Receptor - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Sarcoidosis - immunology; Sarcoidosis - metabolism; Sarcoidosis - pathology; Signal Transduction; TOR Serine-Threonine Kinases - metabolism; Young Adult; lymphocyte cell-specific protein-tyrosine kinase; AKT; sarcoidosis; programmed death-1; proliferation; phosphatidylinositol 3-kinase