Planar chromatographic super-hyphenations for rapid dereplication

• Published in: Phytochemistry reviews Vol. 24; no. 1; pp. 1 - 12
• Main Author: Morlock, Gertrud E.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.02.2025; Springer Nature B.V
• Subjects: Analytical chemistry; Artificial intelligence; Bioassays; Biochemistry; Biological effects; Biology; Biomedical and Life Sciences; Chemistry; Chemistry/Food Science; Chromatography; Column chromatography; digestion; humans; Life Sciences; liver; Mass spectrometry; Mass spectroscopy; Mixtures; Multiplexing; Organic Chemistry; Plant Genetics and Genomics; Plant Sciences; prioritization; Separation; Thin layer chromatography; variance; Prioritization; Metabolization; Digestion; Citizen science; Bioactivity profiling; Biotransformation

Analytical chemistry offers important tools that provide insight and step-by-step understanding. However, natural samples containing many thousands of different compounds are subject to natural variance which makes it complex for artificial intelligence and human understanding. Instead of the prevai...