Validating the accuracy of mathematical model–based pharmacogenomics dose prediction with real-world data - Saab, Yolande; Nakad, Zahi (European journal of clinical pharmacology, 2025)
Keywords: Artificial intelligence; Biomedical and Life Sciences; Biomedicine; CYP2D6 protein; Cytochrome P-450 CYP2C19 - genetics; Cytochrome P-450 CYP2D6 - genetics; Cytochrome P450; Decision making; Dosage; Dose-Response Relationship, Drug; Drug dosages; Gene polymorphism; Genotype; Humans; Mathematical models; Models, Theoretical; Patients; Pharmaceutical Preparations - administration & dosage; Pharmaceutical Preparations - metabolism; Pharmacogenetics - methods; Pharmacogenomics; Pharmacology/Toxicology; Phenotypes; Polymorphism, Genetic; Allele activity; Dose prediction; Cytochrome P450; Drug metabolism; Genotype; Personalized medicine; Artificial intelligence