BAG3’s dual roles in Parkinson’s disease and cardiomyopathy: benefit or liability?
Saved in:
Published in | Acta neuropathologica Vol. 148; no. 1; p. 71 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Berlin/Heidelberg
Springer Berlin Heidelberg
25.11.2024
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
Cover
Loading…
ArticleNumber | 71 |
---|---|
Author | Hakonarson, Hakon Qu, Hui-Qi |
Author_xml | – sequence: 1 givenname: Hui-Qi surname: Qu fullname: Qu, Hui-Qi organization: The Center for Applied Genomics, Children’s Hospital of Philadelphia – sequence: 2 givenname: Hakon surname: Hakonarson fullname: Hakonarson, Hakon email: hakonarson@chop.edu organization: The Center for Applied Genomics, Children’s Hospital of Philadelphia, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Division of Human Genetics, Children’s Hospital of Philadelphia, Division of Pulmonary Medicine, Children’s Hospital of Philadelphia, Faculty of Medicine, University of Iceland |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39585448$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kc9O3DAQxq2Kqstu-wIckCUuXNL6X5yEC1pWsFRaqT20vVoTxwFD1l7s5LA3XoPX40lwmwUqDkgeeaT5fTOj-aZoz3lnEDqg5CslpPgWCRGEZoSJFCUvMvEB7VPBWUZyzvf-yydoGuMNIZQVIv-EJrzKy1yIch_9OZsv-eP9Q8TNAB0OvjMRW4d_Qri1Lno31mw0EA0G12ANobF-vfUb6K-3J7g2zrS2xz7gzkJtO9tvTz-jjy100XzZ_TP0--L81-IyW_1Yfl_MV5nmTPYZA1JWFa8laCkIqeomh1IT0KWUBmqoBKdcFgVtcinztizS0waIZJVmgrZ8ho7Hvpvg7wYTe7W2UZuuA2f8EFWSM0mZTENm6OgNeuOH4NJ2I1VJXuaJOtxRQ702jdoEu4awVc8XSwAbAR18jMG0Lwgl6q8tarRFJVvUP1uUSCI-imKC3ZUJr7PfUT0BoemO7A |
Cites_doi | 10.1186/s13024-023-00699-0 10.1006/bbrc.2001.5512 10.3390/ijms252011308 10.1038/emboj.2009.29 10.15252/emmm.202114712 10.3389/fnana.2016.00128 10.1093/brain/awf080 10.21037/atm-22-5159 10.1038/s41593-022-01061-1 10.1007/978-981-15-4272-5_2 10.1007/s00281-022-00947-3 10.1016/j.jacbts.2017.09.009 10.1038/sj.onc.1202334 10.1016/j.mito.2012.06.004 10.1093/braincomms/fcac165 10.1016/j.neurobiolaging.2020.12.013 10.1002/1873-3468.12751 10.1016/j.neurobiolaging.2017.12.001 10.1007/s00401-024-02810-1 10.1002/humu.21603 10.1016/S0278-5846(03)00019-8 10.1002/alz.066654 10.1016/j.ymthe.2022.08.003 10.1016/j.neuron.2023.05.006 10.1016/j.jmb.2016.11.013 10.2174/1871527317666180816100203 10.1021/acschemneuro.8b00356 10.3389/fnmol.2016.00157 10.1007/s10048-006-0032-6 10.1016/j.biopsych.2020.01.026 10.3389/fnmol.2017.00177 10.3390/cancers14174168 10.1093/nar/gkt439 10.1016/s1474-4422(19)30320-5 10.1038/s41588-020-00762-2 10.1074/jbc.274.2.781 10.3390/cells9030574 10.1093/eurheartj/ehr105 10.1016/j.neurobiolaging.2017.08.023 10.1038/348334a0 10.3390/cells10102638 10.1016/j.biopsych.2021.10.024 10.1016/j.ajpath.2016.03.017 10.1006/excr.1996.0070 10.1016/S0304-3835(02)00456-1 10.1161/JAHA.122.027373 10.15252/embj.201593378 10.1038/s41593-018-0298-7 10.1080/15548627.2023.2276622 |
ContentType | Journal Article |
Copyright | The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024 The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. |
Copyright_xml | – notice: The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024 – notice: The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. |
DBID | AAYXX CITATION NPM 7TK 7U9 H94 K9. 7X8 |
DOI | 10.1007/s00401-024-02837-4 |
DatabaseName | CrossRef PubMed Neurosciences Abstracts Virology and AIDS Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
DatabaseTitle | CrossRef PubMed AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Virology and AIDS Abstracts Neurosciences Abstracts MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1432-0533 |
ExternalDocumentID | 39585448 10_1007_s00401_024_02837_4 |
Genre | Letter Correspondence |
GrantInformation_xml | – fundername: Children's Hospital of Philadelphia |
GroupedDBID | --- -53 -5E -5G -BR -EM -~C .86 .VR 06C 06D 0R~ 0VY 199 1N0 203 23M 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2~H 30V 36B 4.4 406 408 409 40D 40E 5GY 5RE 5VS 67Z 6NX 78A 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANZL AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYZH ABAKF ABBBX ABBXA ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABIVO ABJNI ABJOX ABKCH ABKTR ABLJU ABMNI ABMQK ABNWP ABPLI ABQBU ABSXP ABTEG ABTKH ABTMW ABUWZ ABWNU ABXPI ACAOD ACDTI ACGFS ACHSB ACHVE ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACZOJ ADBBV ADHHG ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEFQL AEGAL AEGNC AEJHL AEJRE AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BENPR BGNMA BSONS CS3 CSCUP DDRTE DL5 DNIVK DPUIP EBLON EBS EIOEI ESBYG F5P FEDTE FERAY FFXSO FIGPU FNLPD FRRFC FWDCC G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GXS HF~ HG5 HG6 HMJXF HQYDN HRMNR HVGLF HZ~ I09 IAO IHE IHR IJ- IKXTQ IMOTQ INH IPY ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KPH L7B LAS LLZTM M4Y MA- NB0 NPVJJ NQJWS NU0 O93 O9G O9I O9J OAM P19 P2P P9S PF0 PT4 PT5 QOK QOR QOS R89 R9I RHV ROL RPX RRX RSV S16 S27 S37 S3B SAP SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SZ9 SZN T13 TSG TSK TSV TT1 TUC U2A U9L UG4 UOJIU UTJUX VC2 W23 W48 WH7 WJK WK8 YLTOR Z45 Z7U Z7V Z81 Z82 Z83 Z87 Z8O Z8P Z8U Z8V Z8W Z91 ZOVNA ~EX AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC AEZWR AFDZB AFHIU AFOHR AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION ABRTQ NPM 7TK 7U9 H94 K9. 7X8 |
ID | FETCH-LOGICAL-c326t-2a08993b6ac64009bd5a8c0ac866eaba943136771d5665f87f87cea0629c241f3 |
IEDL.DBID | U2A |
ISSN | 1432-0533 0001-6322 |
IngestDate | Thu Jul 10 23:54:12 EDT 2025 Sat Aug 16 19:42:35 EDT 2025 Mon Jul 21 05:55:37 EDT 2025 Tue Jul 01 03:50:48 EDT 2025 Fri Feb 21 02:38:40 EST 2025 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 1 |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c326t-2a08993b6ac64009bd5a8c0ac866eaba943136771d5665f87f87cea0629c241f3 |
Notes | SourceType-Scholarly Journals-1 ObjectType-Correspondence-1 content type line 14 content type line 23 |
PMID | 39585448 |
PQID | 3132696385 |
PQPubID | 49178 |
ParticipantIDs | proquest_miscellaneous_3132612699 proquest_journals_3132696385 pubmed_primary_39585448 crossref_primary_10_1007_s00401_024_02837_4 springer_journals_10_1007_s00401_024_02837_4 |
ProviderPackageCode | CITATION AAYXX |
PublicationCentury | 2000 |
PublicationDate | 2024-11-25 |
PublicationDateYYYYMMDD | 2024-11-25 |
PublicationDate_xml | – month: 11 year: 2024 text: 2024-11-25 day: 25 |
PublicationDecade | 2020 |
PublicationPlace | Berlin/Heidelberg |
PublicationPlace_xml | – name: Berlin/Heidelberg – name: Germany – name: Heidelberg |
PublicationSubtitle | Pathology and Mechanisms of Neurological Disease |
PublicationTitle | Acta neuropathologica |
PublicationTitleAbbrev | Acta Neuropathol |
PublicationTitleAlternate | Acta Neuropathol |
PublicationYear | 2024 |
Publisher | Springer Berlin Heidelberg Springer Nature B.V |
Publisher_xml | – name: Springer Berlin Heidelberg – name: Springer Nature B.V |
References | Qu, Wang, Rosa-Campos, Hakonarson, Feldman (CR28) 2024; 25 Smeland, Shadrin, Bahrami, Broce, Tesli, Frei (CR37) 2021; 89 Luthold, Lambert, Guilbert, Rodrigue, Fuchs, Varlet (CR23) 2021; 10 Hwu, Kiening, Anselm, Compton, Nakajima, Opladen (CR13) 2021; 13 Martirosyan, Ansari, Pestana, Hebestreit, Gasparyan, Aleksanyan (CR24) 2024; 19 Kulkarni, Burns, Brundin, Wesson (CR16) 2022 Sweeney, Kim, Morrison, Li, Acosta, Liang (CR39) 2024; 148 Samali, Cotter (CR35) 1996; 223 Rocco, Akhter, Ehrlich, Scott, Lungu, Munjal (CR32) 2022 Fu, Possenti, Freer, Nakano, Hernandez Villegas, Tang (CR9) 2019; 22 Stürner, Behl (CR38) 2017 Morrison, Li, Liang, Chen, Acosta, Fitzgerald (CR25) 2022; 18 Tang, Ji, Pallo, Rahman, Johnson (CR42) 2018; 63 Kumar, Dhawan, Kadam, Shinde (CR17) 2018; 17 Blits, Petry (CR5) 2016; 10 Bekker, Abrahams, Loos, Bardien (CR4) 2021; 100 Zhou, Chng (CR47) 2013; 13 Lev, Melamed, Offen (CR18) 2003; 27 Gamerdinger, Hajieva, Kaya, Wolfrum, Hartl, Behl (CR10) 2009; 28 Avinery, Gahramanov, Hesin, Sherman (CR3) 2022; 14 Tadros, Francis, Xu, Vermeer, Harper, Huurman (CR40) 2021; 53 Cao, Yang, Mao, Zhang, Wang, Yang (CR6) 2017; 60 Fernández-Fernández, Gragera, Ochoa-Ibarrola, Quintana-Gallardo, Valpuesta (CR8) 2017; 591 Kögel, Linder, Brunschweiger, Chines, Behl (CR15) 2020; 9 Arimura, Ishikawa, Nunoda, Kawai, Kimura (CR2) 2011; 32 Quintana, Parry, He, Yates, Sidorova, Murray (CR30) 2016; 186 Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer (CR11) 1990; 348 Doong, Vrailas, Kohn (CR7) 2002; 188 Lin, Sandkuhler, Dunlea, Rodwell-Bullock, King, Johnson (CR19) 2024; 20 Sheehan, Nadarajah, Kanan, Patterson, Novotny, Lawrence (CR36) 2023; 111 Żwirowski, Kłosowska, Obuchowski, Nillegoda, Piróg, Ziętkiewicz (CR49) 2017; 36 Wang, Duncan, Shi, Zhang (CR44) 2013; 41 Kamath, Abdulraouf, Burris, Langlieb, Gazestani, Nadaf (CR14) 2022; 25 Villard, Perret, Gary, Proust, Dilanian, Hengstenberg (CR43) 2011; 32 Yamochi, Kaneita, Akiyama, Mori, Moriyama (CR45) 1999; 18 Antoku, Maser, Scully, Delach, Johnson (CR1) 2001; 286 Nalls, Blauwendraat, Vallerga, Heilbron, Bandres-Ciga, Chang (CR27) 2019; 18 Lin, Tang, Ji, Girardi, Cvetojevic, Chen (CR20) 2022; 92 Rauch, Tse, Freilich, Mok, Makley, Southworth (CR31) 2017; 429 Myers, McClung, Wang, Tahrir, Gupta, Gordon (CR26) 2018; 3 Qu, Feldman, Hakonarson (CR29) 2022; 11 Liu, Liu, Yang (CR21) 2019; 10 Ying, Lv, Yao, Dong, Yang, Cao (CR46) 2022; 10 Hughes, Daniel, Ben-Shlomo, Lees (CR12) 2002; 125 Roth, Hevezi, Lee, Willhite, Lechner, Foster (CR33) 2006; 7 Takayama, Xie, Reed (CR41) 1999; 274 Zhu, Yin, Zhao, Zhang (CR48) 2022; 44 Sala, Marinig, Arosio, Ferrarese (CR34) 2016; 9 Lu, Wu, Yue, Le (CR22) 2020 A Kumar (2837_CR17) 2018; 17 A Martirosyan (2837_CR24) 2024; 19 J Wang (2837_CR44) 2013; 41 B Zhu (2837_CR48) 2022; 44 J Liu (2837_CR21) 2019; 10 N Sweeney (2837_CR39) 2024; 148 H-Q Qu (2837_CR28) 2024; 25 M Gamerdinger (2837_CR10) 2009; 28 MT Quintana (2837_CR30) 2016; 186 D Hockenbery (2837_CR11) 1990; 348 B Blits (2837_CR5) 2016; 10 ZM Ying (2837_CR46) 2022; 10 PW-L Hwu (2837_CR13) 2021; 13 T Arimura (2837_CR2) 2011; 32 M Tang (2837_CR42) 2018; 63 T Yamochi (2837_CR45) 1999; 18 N Lev (2837_CR18) 2003; 27 J Zhou (2837_CR47) 2013; 13 J Lu (2837_CR22) 2020 S Takayama (2837_CR41) 1999; 274 RB Roth (2837_CR33) 2006; 7 H Doong (2837_CR7) 2002; 188 A Samali (2837_CR35) 1996; 223 OB Smeland (2837_CR37) 2021; 89 H Lin (2837_CR20) 2022; 92 M Bekker (2837_CR4) 2021; 100 YL Cao (2837_CR6) 2017; 60 MA Nalls (2837_CR27) 2019; 18 S Żwirowski (2837_CR49) 2017; 36 L Avinery (2837_CR3) 2022; 14 HQ Qu (2837_CR29) 2022; 11 AJ Hughes (2837_CR12) 2002; 125 T Kamath (2837_CR14) 2022; 25 K Antoku (2837_CR1) 2001; 286 MT Rocco (2837_CR32) 2022 H Fu (2837_CR9) 2019; 22 G Sala (2837_CR34) 2016; 9 MR Fernández-Fernández (2837_CR8) 2017; 591 C Luthold (2837_CR23) 2021; 10 D Kögel (2837_CR15) 2020; 9 R Tadros (2837_CR40) 2021; 53 VD Myers (2837_CR26) 2018; 3 C Morrison (2837_CR25) 2022; 18 JN Rauch (2837_CR31) 2017; 429 H Lin (2837_CR19) 2024; 20 E Villard (2837_CR43) 2011; 32 E Stürner (2837_CR38) 2017 AS Kulkarni (2837_CR16) 2022 PW Sheehan (2837_CR36) 2023; 111 |
References_xml | – volume: 19 start-page: 7 year: 2024 ident: CR24 article-title: Unravelling cell type-specific responses to Parkinson’s disease at single cell resolution publication-title: Mol Neurodegener doi: 10.1186/s13024-023-00699-0 – volume: 286 start-page: 1003 year: 2001 end-page: 1010 ident: CR1 article-title: Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.2001.5512 – volume: 25 start-page: 11308 year: 2024 ident: CR28 article-title: The role of BAG3 protein interactions in cardiomyopathies publication-title: Int J Mol Sci doi: 10.3390/ijms252011308 – volume: 28 start-page: 889 year: 2009 end-page: 901 ident: CR10 article-title: Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3 publication-title: EMBO J doi: 10.1038/emboj.2009.29 – volume: 13 year: 2021 ident: CR13 article-title: Gene therapy in the putamen for curing AADC deficiency and Parkinson's disease publication-title: EMBO Mol Med doi: 10.15252/emmm.202114712 – volume: 10 start-page: 128 year: 2016 ident: CR5 article-title: Perspective on the road toward gene therapy for Parkinson's disease publication-title: Front Neuroanat doi: 10.3389/fnana.2016.00128 – volume: 125 start-page: 861 year: 2002 end-page: 870 ident: CR12 article-title: The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service publication-title: Brain doi: 10.1093/brain/awf080 – volume: 10 start-page: 1218 year: 2022 ident: CR46 article-title: BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson's disease publication-title: Ann Transl Med doi: 10.21037/atm-22-5159 – volume: 25 start-page: 588 year: 2022 end-page: 595 ident: CR14 article-title: Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease publication-title: Nat Neurosci doi: 10.1038/s41593-022-01061-1 – start-page: 21 year: 2020 end-page: 51 ident: CR22 article-title: Autophagy and Parkinson’s disease publication-title: Autophagy: biology and diseases doi: 10.1007/978-981-15-4272-5_2 – volume: 44 start-page: 659 year: 2022 end-page: 672 ident: CR48 article-title: The immunology of Parkinson's disease publication-title: Seminars Immunopathol doi: 10.1007/s00281-022-00947-3 – volume: 3 start-page: 122 year: 2018 end-page: 131 ident: CR26 article-title: The multifunctional protein BAG3: a novel therapeutic target in cardiovascular disease publication-title: JACC Basic Transl Sci doi: 10.1016/j.jacbts.2017.09.009 – volume: 18 start-page: 487 year: 1999 end-page: 494 ident: CR45 article-title: Adenovirus-mediated high expression of BCL-6 in CV-1 cells induces apoptotic cell death accompanied by down-regulation of BCL-2 and BCL-XL publication-title: Oncogene doi: 10.1038/sj.onc.1202334 – volume: 13 start-page: 163 year: 2013 end-page: 169 ident: CR47 article-title: Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer publication-title: Mitochondrion doi: 10.1016/j.mito.2012.06.004 – year: 2022 ident: CR16 article-title: Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease publication-title: Brain Commun doi: 10.1093/braincomms/fcac165 – volume: 100 start-page: 91 year: 2021 end-page: 105 ident: CR4 article-title: Can the interplay between autophagy and apoptosis be targeted as a novel therapy for Parkinson's disease? publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2020.12.013 – volume: 591 start-page: 2648 year: 2017 end-page: 2660 ident: CR8 article-title: Hsp70–a master regulator in protein degradation publication-title: FEBS Lett doi: 10.1002/1873-3468.12751 – volume: 63 start-page: 128 year: 2018 end-page: 139 ident: CR42 article-title: Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2017.12.001 – volume: 148 start-page: 52 year: 2024 ident: CR39 article-title: Neuronal BAG3 attenuates tau hyperphosphorylation, synaptic dysfunction, and cognitive deficits induced by traumatic brain injury via the regulation of autophagy-lysosome pathway publication-title: Acta Neuropathol doi: 10.1007/s00401-024-02810-1 – volume: 32 start-page: 1481 year: 2011 end-page: 1491 ident: CR2 article-title: Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes publication-title: Hum Mutat doi: 10.1002/humu.21603 – volume: 27 start-page: 245 year: 2003 end-page: 250 ident: CR18 article-title: Apoptosis and Parkinson's disease publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/S0278-5846(03)00019-8 – volume: 18 year: 2022 ident: CR25 article-title: BAG3 attenuates tau hyperphosphorylation and gliosis induced by traumatic brain injury publication-title: Alzheimers Dement doi: 10.1002/alz.066654 – year: 2022 ident: CR32 article-title: Long-term safety of MRI-guided administration of AAV2-GDNF and gadoteridol in the putamen of individuals with Parkinson's disease publication-title: Mol Ther doi: 10.1016/j.ymthe.2022.08.003 – volume: 111 start-page: 2383 year: 2023 end-page: 2398.e2387 ident: CR36 article-title: An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology publication-title: Neuron doi: 10.1016/j.neuron.2023.05.006 – volume: 429 start-page: 128 year: 2017 end-page: 141 ident: CR31 article-title: BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins publication-title: J Mol Biol doi: 10.1016/j.jmb.2016.11.013 – volume: 17 start-page: 696 year: 2018 end-page: 705 ident: CR17 article-title: Autophagy and mitochondria: targets in neurodegenerative disorders publication-title: CNS Neurol Disord-Drug Targets doi: 10.2174/1871527317666180816100203 – volume: 10 start-page: 792 year: 2019 end-page: 802 ident: CR21 article-title: Balancing apoptosis and autophagy for Parkinson's disease therapy: targeting BCL-2 publication-title: ACS Chem Neurosci doi: 10.1021/acschemneuro.8b00356 – volume: 9 start-page: 157 year: 2016 ident: CR34 article-title: Role of chaperone-mediated autophagy dysfunctions in the pathogenesis of Parkinson’s disease publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2016.00157 – volume: 7 start-page: 67 year: 2006 end-page: 80 ident: CR33 article-title: Gene expression analyses reveal molecular relationships among 20 regions of the human CNS publication-title: Neurogenetics doi: 10.1007/s10048-006-0032-6 – volume: 89 start-page: 227 year: 2021 end-page: 235 ident: CR37 article-title: Genome-wide association analysis of Parkinson's disease and schizophrenia reveals shared genetic architecture and identifies novel risk loci publication-title: Biol Psychiat doi: 10.1016/j.biopsych.2020.01.026 – year: 2017 ident: CR38 article-title: The role of the multifunctional BAG3 protein in cellular protein quality control and in disease publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2017.00177 – volume: 14 start-page: 4168 year: 2022 ident: CR3 article-title: Hsp70–Bag3 module regulates macrophage motility and tumor infiltration via transcription factor LITAF and CSF1 publication-title: Cancers doi: 10.3390/cancers14174168 – volume: 41 start-page: W77 year: 2013 end-page: W83 ident: CR44 article-title: WEB-based gene set analysis toolkit (WebGestalt): update 2013 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkt439 – volume: 18 start-page: 1091 year: 2019 end-page: 1102 ident: CR27 article-title: Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies publication-title: Lancet Neurol doi: 10.1016/s1474-4422(19)30320-5 – volume: 53 start-page: 128 year: 2021 end-page: 134 ident: CR40 article-title: Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect publication-title: Nat Genet doi: 10.1038/s41588-020-00762-2 – volume: 274 start-page: 781 year: 1999 end-page: 786 ident: CR41 article-title: An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators publication-title: J Biol Chem doi: 10.1074/jbc.274.2.781 – volume: 9 start-page: 574 year: 2020 ident: CR15 article-title: At the crossroads of apoptosis and autophagy: multiple roles of the co-chaperone BAG3 in stress and therapy resistance of cancer publication-title: Cells doi: 10.3390/cells9030574 – volume: 32 start-page: 1065 year: 2011 end-page: 1076 ident: CR43 article-title: A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy publication-title: Eur Heart J doi: 10.1093/eurheartj/ehr105 – volume: 60 start-page: 104 year: 2017 end-page: 115 ident: CR6 article-title: A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2017.08.023 – volume: 348 start-page: 334 year: 1990 end-page: 336 ident: CR11 article-title: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death publication-title: Nature doi: 10.1038/348334a0 – volume: 10 start-page: 2638 year: 2021 ident: CR23 article-title: CDK1-mediated phosphorylation of BAG3 promotes mitotic cell shape remodeling and the molecular assembly of mitotic p62 bodies publication-title: Cells doi: 10.3390/cells10102638 – volume: 92 start-page: 10 year: 2022 end-page: 24 ident: CR20 article-title: BAG3 regulation of RAB35 mediates the endosomal sorting complexes required for transport/endolysosome pathway and tau clearance publication-title: Biol Psychiat doi: 10.1016/j.biopsych.2021.10.024 – volume: 186 start-page: 1989 year: 2016 end-page: 2007 ident: CR30 article-title: Cardiomyocyte-specific human Bcl2-associated anthanogene 3 P209L expression induces mitochondrial fragmentation, Bcl2-associated anthanogene 3 haploinsufficiency, and activates p38 signaling publication-title: Am J Pathol doi: 10.1016/j.ajpath.2016.03.017 – volume: 223 start-page: 163 year: 1996 end-page: 170 ident: CR35 article-title: Heat shock proteins increase resistance to apoptosis publication-title: Exp Cell Res doi: 10.1006/excr.1996.0070 – volume: 188 start-page: 25 year: 2002 end-page: 32 ident: CR7 article-title: What's in the ‘BAG’?—a functional domain analysis of the BAG-family proteins publication-title: Cancer Lett doi: 10.1016/S0304-3835(02)00456-1 – volume: 11 year: 2022 ident: CR29 article-title: Genetics of BAG3: a paradigm for developing precision therapies for dilated cardiomyopathies publication-title: J Am Heart Assoc doi: 10.1161/JAHA.122.027373 – volume: 36 start-page: 783 year: 2017 end-page: 796 ident: CR49 article-title: Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding publication-title: EMBO J doi: 10.15252/embj.201593378 – volume: 22 start-page: 47 year: 2019 end-page: 56 ident: CR9 article-title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology publication-title: Nat Neurosci doi: 10.1038/s41593-018-0298-7 – volume: 20 start-page: 577 year: 2024 end-page: 589 ident: CR19 article-title: BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1 publication-title: Autophagy doi: 10.1080/15548627.2023.2276622 – volume: 89 start-page: 227 year: 2021 ident: 2837_CR37 publication-title: Biol Psychiat doi: 10.1016/j.biopsych.2020.01.026 – volume: 11 year: 2022 ident: 2837_CR29 publication-title: J Am Heart Assoc doi: 10.1161/JAHA.122.027373 – volume: 100 start-page: 91 year: 2021 ident: 2837_CR4 publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2020.12.013 – volume: 10 start-page: 128 year: 2016 ident: 2837_CR5 publication-title: Front Neuroanat doi: 10.3389/fnana.2016.00128 – volume: 13 year: 2021 ident: 2837_CR13 publication-title: EMBO Mol Med doi: 10.15252/emmm.202114712 – volume: 41 start-page: W77 year: 2013 ident: 2837_CR44 publication-title: Nucleic Acids Res doi: 10.1093/nar/gkt439 – volume: 125 start-page: 861 year: 2002 ident: 2837_CR12 publication-title: Brain doi: 10.1093/brain/awf080 – volume: 9 start-page: 574 year: 2020 ident: 2837_CR15 publication-title: Cells doi: 10.3390/cells9030574 – volume: 53 start-page: 128 year: 2021 ident: 2837_CR40 publication-title: Nat Genet doi: 10.1038/s41588-020-00762-2 – volume: 188 start-page: 25 year: 2002 ident: 2837_CR7 publication-title: Cancer Lett doi: 10.1016/S0304-3835(02)00456-1 – volume: 7 start-page: 67 year: 2006 ident: 2837_CR33 publication-title: Neurogenetics doi: 10.1007/s10048-006-0032-6 – volume: 22 start-page: 47 year: 2019 ident: 2837_CR9 publication-title: Nat Neurosci doi: 10.1038/s41593-018-0298-7 – volume: 14 start-page: 4168 year: 2022 ident: 2837_CR3 publication-title: Cancers doi: 10.3390/cancers14174168 – volume: 348 start-page: 334 year: 1990 ident: 2837_CR11 publication-title: Nature doi: 10.1038/348334a0 – volume: 10 start-page: 2638 year: 2021 ident: 2837_CR23 publication-title: Cells doi: 10.3390/cells10102638 – volume: 44 start-page: 659 year: 2022 ident: 2837_CR48 publication-title: Seminars Immunopathol doi: 10.1007/s00281-022-00947-3 – volume: 13 start-page: 163 year: 2013 ident: 2837_CR47 publication-title: Mitochondrion doi: 10.1016/j.mito.2012.06.004 – volume: 10 start-page: 792 year: 2019 ident: 2837_CR21 publication-title: ACS Chem Neurosci doi: 10.1021/acschemneuro.8b00356 – volume: 63 start-page: 128 year: 2018 ident: 2837_CR42 publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2017.12.001 – volume: 27 start-page: 245 year: 2003 ident: 2837_CR18 publication-title: Prog Neuropsychopharmacol Biol Psychiatry doi: 10.1016/S0278-5846(03)00019-8 – volume: 19 start-page: 7 year: 2024 ident: 2837_CR24 publication-title: Mol Neurodegener doi: 10.1186/s13024-023-00699-0 – volume: 9 start-page: 157 year: 2016 ident: 2837_CR34 publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2016.00157 – volume: 18 start-page: 1091 year: 2019 ident: 2837_CR27 publication-title: Lancet Neurol doi: 10.1016/s1474-4422(19)30320-5 – volume: 18 start-page: 487 year: 1999 ident: 2837_CR45 publication-title: Oncogene doi: 10.1038/sj.onc.1202334 – volume: 17 start-page: 696 year: 2018 ident: 2837_CR17 publication-title: CNS Neurol Disord-Drug Targets doi: 10.2174/1871527317666180816100203 – volume: 223 start-page: 163 year: 1996 ident: 2837_CR35 publication-title: Exp Cell Res doi: 10.1006/excr.1996.0070 – volume: 60 start-page: 104 year: 2017 ident: 2837_CR6 publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2017.08.023 – volume: 32 start-page: 1481 year: 2011 ident: 2837_CR2 publication-title: Hum Mutat doi: 10.1002/humu.21603 – volume: 429 start-page: 128 year: 2017 ident: 2837_CR31 publication-title: J Mol Biol doi: 10.1016/j.jmb.2016.11.013 – volume: 591 start-page: 2648 year: 2017 ident: 2837_CR8 publication-title: FEBS Lett doi: 10.1002/1873-3468.12751 – volume: 36 start-page: 783 year: 2017 ident: 2837_CR49 publication-title: EMBO J doi: 10.15252/embj.201593378 – volume: 25 start-page: 588 year: 2022 ident: 2837_CR14 publication-title: Nat Neurosci doi: 10.1038/s41593-022-01061-1 – start-page: 21 volume-title: Autophagy: biology and diseases year: 2020 ident: 2837_CR22 doi: 10.1007/978-981-15-4272-5_2 – year: 2022 ident: 2837_CR16 publication-title: Brain Commun doi: 10.1093/braincomms/fcac165 – volume: 20 start-page: 577 year: 2024 ident: 2837_CR19 publication-title: Autophagy doi: 10.1080/15548627.2023.2276622 – year: 2022 ident: 2837_CR32 publication-title: Mol Ther doi: 10.1016/j.ymthe.2022.08.003 – volume: 274 start-page: 781 year: 1999 ident: 2837_CR41 publication-title: J Biol Chem doi: 10.1074/jbc.274.2.781 – volume: 32 start-page: 1065 year: 2011 ident: 2837_CR43 publication-title: Eur Heart J doi: 10.1093/eurheartj/ehr105 – volume: 286 start-page: 1003 year: 2001 ident: 2837_CR1 publication-title: Biochem Biophys Res Commun doi: 10.1006/bbrc.2001.5512 – volume: 25 start-page: 11308 year: 2024 ident: 2837_CR28 publication-title: Int J Mol Sci doi: 10.3390/ijms252011308 – volume: 3 start-page: 122 year: 2018 ident: 2837_CR26 publication-title: JACC Basic Transl Sci doi: 10.1016/j.jacbts.2017.09.009 – volume: 186 start-page: 1989 year: 2016 ident: 2837_CR30 publication-title: Am J Pathol doi: 10.1016/j.ajpath.2016.03.017 – volume: 111 start-page: 2383 year: 2023 ident: 2837_CR36 publication-title: Neuron doi: 10.1016/j.neuron.2023.05.006 – volume: 18 year: 2022 ident: 2837_CR25 publication-title: Alzheimers Dement doi: 10.1002/alz.066654 – year: 2017 ident: 2837_CR38 publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2017.00177 – volume: 92 start-page: 10 year: 2022 ident: 2837_CR20 publication-title: Biol Psychiat doi: 10.1016/j.biopsych.2021.10.024 – volume: 28 start-page: 889 year: 2009 ident: 2837_CR10 publication-title: EMBO J doi: 10.1038/emboj.2009.29 – volume: 10 start-page: 1218 year: 2022 ident: 2837_CR46 publication-title: Ann Transl Med doi: 10.21037/atm-22-5159 – volume: 148 start-page: 52 year: 2024 ident: 2837_CR39 publication-title: Acta Neuropathol doi: 10.1007/s00401-024-02810-1 |
SSID | ssj0012745 |
Score | 2.4467754 |
SourceID | proquest pubmed crossref springer |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 71 |
SubjectTerms | Cardiomyopathy Correspondence Medicine Medicine & Public Health Neurodegenerative diseases Neurosciences Parkinson's disease Pathology |
Title | BAG3’s dual roles in Parkinson’s disease and cardiomyopathy: benefit or liability? |
URI | https://link.springer.com/article/10.1007/s00401-024-02837-4 https://www.ncbi.nlm.nih.gov/pubmed/39585448 https://www.proquest.com/docview/3132696385 https://www.proquest.com/docview/3132612699 |
Volume | 148 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEB58gHgR39YXEbxpYNsm2caL7IqrKHpyRU8lr8KCdmV3PezNv-Hf85c46UtEPQiFHjJ9MJlkZvjmmwAcZtKi04gFlUomlHHFaGIjTVnmEq4jHmvj2cg3t-Kyz64e-ENFChvX1e41JFns1A3Zzdsbpr4Ro94ntimbhXmOubsv5OpHnQY7wDyLV_SY35_77oJ-xJU_MNHC1fSWYamKEUmnnNQVmHH5KizcVCj4Gtx3Oxfxx9v7mHgiFfEFgmMyyIlnMBdkrnKshF6Iyi0xRdXp83ToDyCenhCNO1w2mJDhiDwNyk7d09N16PfO784uaXU-AjUYdE1opDxmF2uhjMClKLXlKjEtZRIhnNJKYnAQi3Y7tBiz8Sxp42WcaolIGnTcWbwBc_kwd1tAlLTMZk6GWeaYbcWaaZ6ExjqmWtyGYQBHtcrSl7INRto0PC4UnKKC00LBKQtgt9ZqWi2Jcep7RAq_3HkAB80wGrNHKFTuhq-VTIhiMoDNcjaaz8USMxtMJgM4rqfn6-V__8v2_8R3YDHyphKGNOK7MDcZvbo9DDsmeh_mO71u99bfLx6vz_cLq_sE7k3TOQ |
linkProvider | Springer Nature |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1LTxsxEB5RkNpeUOkDlgI1UntqLWW9trNGqlDKo-ERTqTitvi1UqSyQSQI5cbf6J1fxi9hvK-qoj30gLQ3W15rZuyZ0TffGOBjrhw6jURSpVVKudCcpo4ZynOfCsNEYmxgIw9OZH_ID8_E2RzcNVyYstq9gSTLm7oluwV7w9SXcRp8YpfyupTyyM9uMFGbfD3YRa1-Ymx_73SnT-u3BKjFAGVKmQ74VmKkthLNVhkndGo72qZSem20QkeayG43dhjfiDzt4me97kimLDq5PMF1n8ECBh9pODtD1muxCszrRE3H-fs-_3R5j-LYRxhs6dr2X8FiHZOSXmVESzDni9fwfFCj7m_gx7fe9-T-9teEBOIWCQWJEzIqSGBMl-SxaqyCeoguHLFllevFbBwePJ5tEYM3aj6akvEV-TmqOoPPtt_C8Elk-A7mi3HhV4Bo5bjLvYrz3HPXSQw3Io2t81x3hIvjCD43Issuq7YbWdtguRRwhgLOSgFnPIK1RqpZfQQnWehJKcP1IiLYbIfx8ARERBd-fF3PiXGaimC50kb7u0RhJoXJawRfGvX8Xvzfe1n9v-kf4EX_dHCcHR-cHL2HlyyYTRxTJtZgfnp17dcx5JmajdLiCJw_tYk_AIoZDFM |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3NahRBEC5ihOBFTPybGE0LetImOz3dvdOCyGqyJsYED67kNvYvLJjZJTtB9uZr-BY-k0-S6vkTSTx4CMytm56mqrqriq--aoBnQTl0GpmkSquccqE5zR0zlAefC8NEZmxkIx8dy_0J_3AiTlbgV8eFqavdO0iy4TTELk1ltTN3YacnvkXbwzSYcRr945Dytqzy0C-_Y9K2eH2wixp-zth47_O7fdq-K0AtBisVZTpiXZmR2ko0YWWc0LkdaJtL6bXRCp1qJofD1GGsI0I-xM96PZBMWXR4IcN1b8BNHtnHeIImbNTjFpjjiZaac_U-_3Z_l2LaS3hs7ebGd-B2G5-SUWNQ67Diyw1YO2oR-Lvw5e3offb7x88FiSQuEosTF2RaksierolkzVgD-xBdOmLritfT5Sw-frx8RQzermFakdkZ-TZtuoQv39yDybXI8D6slrPSPwSileMueJWG4LkbZIYbkafWea4HwqVpAi86kRXzpgVH0TdbrgVcoICLWsAFT2Crk2rRHsdFEftTynjViASe9sN4kCI6oks_O2_npDhNJfCg0Ub_u0xhVoWJbAIvO_X8Wfzfe9n8v-nbsPZpd1x8PDg-fAS3WLSaNKVMbMFqdXbuH2P0U5kntcER-HrdFn4BRM4Qhg |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=BAG3%E2%80%99s+dual+roles+in+Parkinson%E2%80%99s+disease+and+cardiomyopathy%3A+benefit+or+liability%3F&rft.jtitle=Acta+neuropathologica&rft.au=Qu%2C+Hui-Qi&rft.au=Hakonarson%2C+Hakon&rft.date=2024-11-25&rft.pub=Springer+Berlin+Heidelberg&rft.eissn=1432-0533&rft.volume=148&rft.issue=1&rft_id=info:doi/10.1007%2Fs00401-024-02837-4&rft.externalDocID=10_1007_s00401_024_02837_4 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1432-0533&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1432-0533&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1432-0533&client=summon |