The spectrum of histopathological findings after SVR to DAA for recurrent HCV infection in liver transplant recipients

• Published in: Virchows Archiv : an international journal of pathology Vol. 480; no. 2; pp. 335 - 347
• Main Authors: Sanghi, Vedha, Romero-Marrero, Carlos, Flocco, Gianina, Graham, Rondell P., Abduljawad, Baraa, Niyazi, Fadi, Asfari, Mohammad M., Hashimoto, Koji, Eghtesad, Bijan, Menon, K. V. Narayanan, Aucejo, Federico N., Lopez, Rocio, Yerian, Lisa M., Allende, Daniela S.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2022; Springer Nature B.V
• Subjects: Allografts; Antiviral agents; Antiviral Agents - therapeutic use; Antiviral drugs; Biopsy; Female; Fibrosis; Hepacivirus; Hepatitis C; Hepatitis C - drug therapy; Hepatitis C - pathology; Hepatitis C, Chronic - drug therapy; Histology; Humans; Hybridization; Inflammation; Interferon; Liver; Liver transplantation; Liver Transplantation - adverse effects; Liver transplants; Medicine; Medicine & Public Health; Middle Aged; Original Article; Pathology; Patients; Recurrent infection; Retrospective Studies; Ribavirin; Statistical analysis; Treatment Outcome; Hepatitis; RNA in situ hybridization; Antiviral; Allograft; Liver

Sustained virological response (SVR) to the treatment of recurrent HCV in liver transplant recipients has excellent clinical outcomes; however, little is known about the effects on allograft histology. The study aimed to assess the histology of the allograft liver. In this single-center, retrospecti...