Pharmacokinetic/pharmacodynamic data extrapolation models for improved pediatric efficacy and toxicity estimation, with application to secondary hyperparathyroidism - Basu, Cynthia; Ma, Xiaoye; Mo, May; Xia, Hong Amy; Brundage, Richard; Al‐Kofahi, Mahmoud; Carlin, Bradley P. (Pharmaceutical statistics : the journal of the pharmaceutical industry, 2020)
Keywords: Adults; clinical trials; Drug development; hierarchical Bayesian model; pediatric drug development; Pediatrics; pharmacodynamic modeling; Pharmacodynamics; pharmacokinetic modeling; Pharmacokinetics; Regulatory approval