Isolation and digital counting of extracellular vesicles from blood via membrane-integrated microfluidics

• Published in: Sensors and actuators. B, Chemical Vol. 358; p. 131473
• Main Authors: Chen, Yi-Sin, Chen, Chihchen, Lai, Charles Pin-Kuang, Lee, Gwo-Bin
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.05.2022; Elsevier Science Ltd
• Subjects: Aluminum oxide; Biomarker; Biomarkers; Blood; Body fluids; Extracellular vesicle; Extracellular vesicles; Fluorescence; Membranes; Microfluidics; Nucleic acids; Proteins; Quantification; Vesicles; Biomarker; Membranes; Quantification; Extracellular vesicle; Microfluidics

Extracellular vesicles (EVs), existing in body fluids, have exhibited a significant potential in clinical diagnostics since many harbor biomarkers specific to certain diseases. Therefore, platforms capable of isolating EVs and quantifying these disease-associated proteins and nucleic acids are under...