Decreased serum glucose levels after initiation of methylphenidate in a patient status post-cerebellar tumour resection: a potential interaction with glipizide

• Published in: Clinical drug investigation Vol. 27; no. 10; pp. 719 - 725
• Main Authors: Gontkovsky, Samuel T, Nevels, Robert, McDonald, Nicholas B, Winkelmann, Michael H
• Format: Journal Article
• Language: English
• Published: New Zealand Wolters Kluwer Health, Inc 01.01.2007
• Subjects: Adult; Blood Glucose - drug effects; Central Nervous System Stimulants - pharmacology; Cerebellar Neoplasms - surgery; Cognition Disorders - drug therapy; Diabetes Mellitus, Type 2 - drug therapy; Drug Interactions; Drug Labeling; Female; Glipizide - pharmacology; Humans; Methylphenidate - pharmacology; Risk Management; Sulfonylurea Compounds - pharmacology; United States; United States Food and Drug Administration; United States

Pharmacological intervention with methylphenidate to address the neurobehavioural deficits associated with various neurological disorders has increased during the past decade. One potential effect of methylphenidate use is its possible influence on serum glucose. This case report illustrates a signi...