Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes - Sarai, Nicholas S.; Fulton, Tyler J.; O’Meara, Ryen L.; Johnston, Kadina E.; Brinkmann-Chen, Sabine; Maar, Ryan R.; Tecklenburg, Ron E.; Roberts, John M.; Reddel, Jordan C. T.; Katsoulis, Dimitris E.; Arnold, Frances H. (Science (American Association for the Advancement of Science), 2024)
Keywords: Bioaccumulation; Carbon; Cleavage; Consumer products; Cytochrome P450; Cytochromes P450; Directed evolution; Evolution; Hydroxylation; Multidisciplinary Sciences; Organosilicon compounds; Oxidation; Science & Technology; Science & Technology - Other Topics; Silicon; Siloxanes; OCTAMETHYLCYCLOTETRASILOXANE; CYTOCHROME-P450; METABOLITES; KINETICS; VOLATILE METHYL SILOXANES