A double point mutation of SOD1 targeting net charge promotes aggregation under destabilizing conditions: Correlation of charge distribution and ALS-provoking mutation - Mavadat, Elaheh; Seyedalipour, Bagher; Hosseinkhani, Saman (Biochimica et biophysica acta. General subjects, 2023)
Keywords: Amyloid; Amyloid - metabolism; Amyloidogenic Proteins; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Amyotrophic Lateral Sclerosis - metabolism; Humans; Mutation; Net charge; Neurodegeneration; Point Mutation; Protein aggregation; Superoxide Dismutase - metabolism; Superoxide dismutase 1; Superoxide Dismutase-1 - genetics; Net charge; Amyotrophic lateral sclerosis; Protein aggregation; Amyloid; Neurodegeneration; Superoxide dismutase 1