Different effects of chronic omeprazole use on osteoporotic fractures rate in the elderly

• Published in: British journal of clinical pharmacology Vol. 89; no. 12; pp. 3539 - 3550
• Main Authors: Gingold‐Belfer, Rachel, Beloosesky, Yichayaou, Amara, Amir, Sharon, Eran, Boltin, Doron, Koren‐Morag, Nira, Meyerovitch, Joseph, Schmilovitz‐Weiss, Hemda
• Format: Journal Article
• Language: English
• Published: England 01.12.2023
• Subjects: Aged; Aged, 80 and over; elders; Female; Hip Fractures - epidemiology; Hip Fractures - etiology; Humans; Male; Omeprazole - adverse effects; omeprazole use; osteoporotic fractures; Osteoporotic Fractures - epidemiology; Osteoporotic Fractures - etiology; Osteoporotic Fractures - prevention & control; Retrospective Studies; Risk Factors; Spinal Fractures; omeprazole use; osteoporotic fractures; elders
• ISSN: 0306-5251; 1365-2125; 1365-2125
• DOI: 10.1111/bcp.15847

Aims To investigate the potential association of chronic use of omeprazole with the occurrence of osteoporotic fractures (OF) in community‐dwelling elderly subjects. Methods The cohort consisted of community‐dwelling residents aged >65 years registered with a large health maintenance organization...