4β‐Hydroxywithanolide E selectively induces oxidative DNA damage for selective killing of oral cancer cells - Tang, Jen‐Yang; Huang, Hurng‐Wern; Wang, Hui‐Ru; Chan, Ya‐Ching; Haung, Jo‐Wen; Shu, Chih‐Wen; Wu, Yang‐Chang; Chang, Hsueh‐Wei (Environmental toxicology, 2018)
Keywords: 4β‐hydroxywithanolide E; Acetylcysteine - pharmacology; Antineoplastic Agents, Phytogenic - pharmacology; Cell Line, Tumor; Cell Survival - drug effects; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - metabolism; DNA Breaks, Double-Stranded - drug effects; DNA Damage - drug effects; DNA double strand break; Free Radical Scavengers - pharmacology; Gingival Neoplasms; Humans; Oxidation-Reduction; oxidative DNA damage; Oxidative Stress - drug effects; Plant Extracts - pharmacology; reactive oxygen species; Reactive Oxygen Species - metabolism; selective killing; Signal Transduction; selective killing; 4β-hydroxywithanolide E; DNA double strand break; oxidative DNA damage; reactive oxygen species