Autoantibodies directed against insulin receptor during the course of Castleman disease: a new case reaffirming autoimmune hypoglycemia as a relapse warning signal

• Published in: European journal of case reports in internal medicine Vol. 12; no. 5; p. 005355
• Main Authors: Jannot, Xavier, Auclair, Martine, Martinot, Martin, Maazouzi, Amin, Boutboul, David, Vigouroux, Corinne, Dieudonné, Yannick
• Format: Journal Article
• Language: English
• Published: Italy SMC Media Srl 2025; SMC MEDIA SRL
• Subjects: autoimmune disease; hypoglycemia; multicentric castleman disease; type b insulin resistance syndrome; Multicentric Castleman disease; type B insulin resistance syndrome; autoimmune disease; hypoglycemia

This case study presents the case of a 54-year-old human immunodeficiency virus (HIV)-positive male who developed type B insulin resistance syndrome (TBIRS) in conjunction with a relapse of human herpesvirus 8 (HHV8)-positive multicentric Castleman disease (MCD). This case is only the sixth reported...