In vitro visualization and quantitative characterization of Pseudomonas aeruginosa biofilm growth dynamics on polyether ether ketone

• Published in: Journal of orthopaedic research Vol. 40; no. 10; pp. 2448 - 2456
• Main Authors: Spake, Carole S. L., Berns, Ellis M., Sahakian, Lori, Turcu, Adrian, Clayton, Ahsia, Glasser, Jillian, Barrett, Caitlin, Barber, Douglas, Antoci, Valentin, Born, Christopher T., Garcia, Dioscaris R.
• Format: Journal Article
• Language: English
• Published: United States 01.10.2022
• Subjects: bacterial biofilms; confocal laser scanning microscopy; orthopedic implant; Pseudomonas aeruginosa; scanning electron microscopy; scanning electron microscopy; Pseudomonas aeruginosa; orthopedic implant; bacterial biofilms; confocal laser scanning microscopy

Prevention and treatment of orthopedic device‐related infection (ODRI) is complicated by the formation of bacterial biofilms. Biofilm formation involves dynamic production of macromolecules that contribute to the structure of the biofilm over time. Limitations to clinically relevant and translationa...