A SHORT AND FLEXIBLE ENANTIOSELECTIVE SYNTHESIS OF THE DIDEMNENONES

• Published in: Angewandte Chemie International Edition Vol. 30; no. 2; pp. 191 - 192
• Main Authors: BAUERMEISTER, H, RIECHERS, H, SCHOMBURG, D, WASHAUSEN, P, WINTERFELDT, E
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 01.02.1991
• Subjects: Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Science & Technology

By simple variation of conditions for the elimination reaction, the unsaturated lactones 2 (R = CH = CH2, R' = H) or 2' (R = H, R' = CH = CH2) may be prepared from 1. The reduction of 2 affords, after the removal of the protecting groups, the mixture of epimeric lactols 3a (X = alpha-...