Gicerin, a cell adhesion molecule, promotes the metastasis of lymphoma cells of the chicken

• Published in: Cell and tissue research Vol. 314; no. 3; pp. 389 - 397
• Main Authors: Tsuchiya, Seiichiro, Tsukamoto, Yasuhiro, Furuya, Masaru, Hiroi, Satoshi, Miki, Naomasa, Sasaki, Fumihiko, Taira, Eiichi
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.12.2003
• Subjects: Animals; Avian Proteins; Carrier Proteins - biosynthesis; Carrier Proteins - genetics; Carrier Proteins - pharmacology; CD146 Antigen; Cell Adhesion - drug effects; Cell Adhesion - physiology; Cell Adhesion Molecules - biosynthesis; Cell Adhesion Molecules - genetics; Cell Adhesion Molecules - pharmacology; Cell Line, Tumor; Cell Movement - drug effects; Cell Movement - genetics; Chickens; Disease Models, Animal; DNA, Complementary - genetics; Gene Expression; Lymphoma - genetics; Lymphoma - metabolism; Lymphoma - pathology; Neoplasm Metastasis - genetics; Neoplasm Transplantation; Transfection

Gicerin is an immunoglobulin superfamily cell adhesion molecule purified from chicken gizzards. This molecule displays an adhesive interaction with a laminin-like protein as well as with gicerin itself. Gicerin appears in embryonic tissues and plays a role in chick development through its cell adhes...