Primary hyperaldosteronism presenting with rhabdomyolysis in emergency room – Case report
Primary hyperaldosteronism, is a well-known cause of secondary hypertension, mostly idiopathic hypertension or arising from aldosterone-producing adenomas. It is characterized with resistant hypertension, hypokalemia and metabolic alkalosis related with aldosterone production excess and plasma renin...
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| Published in | Journal of acute disease Vol. 5; no. 3; pp. 264 - 266 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.05.2016
Department of Endocrinology, Ba?gc?lar Training and Research Hospital, Istanbul, Turkey%Department of Radiology, Erciyes University Medical School, Kayseri, Turkey%Department of Endocrinology, Kayseri Training and Research Hospital, Kayseri, Turkey%Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey Wolters Kluwer Medknow Publications |
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| Abstract | Primary hyperaldosteronism, is a well-known cause of secondary hypertension, mostly idiopathic hypertension or arising from aldosterone-producing adenomas. It is characterized with resistant hypertension, hypokalemia and metabolic alkalosis related with aldosterone production excess and plasma renin activity suppression. Hypokalemic rhabdomyolysis usually presents with muscle pain, cramps, fatigability and generalized weakness. Rhabdomyolysis due to hypokalemia is a rare complication of primary hyperaldosteronism reported within a limited number of cases in medical literature. Diagnosis and treatment of primary hyperaldosteronism is fundamentally important because of the probability of certain cure with accurate surgery. Here, we report a 38-year-old female with hypertension related with primary hyperaldosteronism who presented with rhabdomyolysis most likely due to profound hypokalemia. |
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| AbstractList | Primary hyperaldosteronism, is a well-known cause of secondary hypertension, mostly idiopathic hypertension or arising from aldosterone-producing adenomas. It is charac-terized with resistant hypertension, hypokalemia and metabolic alkalosis related with aldosterone production excess and plasma renin activity suppression. Hypokalemic rhabdomyolysis usually presents with muscle pain, cramps, fatigability and generalized weakness. Rhabdomyolysis due to hypokalemia is a rare complication of primary hyperaldosteronism reported within a limited number of cases in medical literature. Diagnosis and treatment of primary hyperaldosteronism is fundamentally important because of the probability of certain cure with accurate surgery. Here, we report a 38-year-old female with hypertension related with primary hyperaldosteronism who pre-sented with rhabdomyolysis most likely due to profound hypokalemia. Primary hyperaldosteronism, is a well-known cause of secondary hypertension, mostly idiopathic hypertension or arising from aldosterone-producing adenomas. It is characterized with resistant hypertension, hypokalemia and metabolic alkalosis related with aldosterone production excess and plasma renin activity suppression. Hypokalemic rhabdomyolysis usually presents with muscle pain, cramps, fatigability and generalized weakness. Rhabdomyolysis due to hypokalemia is a rare complication of primary hyperaldosteronism reported within a limited number of cases in medical literature. Diagnosis and treatment of primary hyperaldosteronism is fundamentally important because of the probability of certain cure with accurate surgery. Here, we report a 38-year-old female with hypertension related with primary hyperaldosteronism who presented with rhabdomyolysis most likely due to profound hypokalemia. |
| Author | Tanrıverdi, Fatih Cakir, Ilkay Senol, Serkan Karaca, Zuleyha Simsek, Yasin Unluhizarci, Kursad |
| AuthorAffiliation | Department of Endocrinology, Ba?gc?lar Training and Research Hospital, Istanbul, Turkey%Department of Radiology, Erciyes University Medical School, Kayseri, Turkey%Department of Endocrinology, Kayseri Training and Research Hospital, Kayseri, Turkey%Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey |
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| Cites_doi | 10.1097/00000441-200308000-00005 10.1210/jc.2014-3663 10.1186/1756-0500-6-155 10.1056/NEJMra1313341 10.1161/01.HYP.0000231552.10054.aa 10.2169/internalmedicine.48.1444 10.4061/2011/624691 10.1007/s00268-005-0594-8 10.5494/wjh.v5.i2.14 10.14310/horm.2002.1385 10.2215/CJN.08580813 10.5603/EP.2013.0011 10.1016/S0140-6736(08)60834-X 10.1016/S0025-6196(12)62114-4 10.1111/j.1524-6175.2005.04144.x 10.1530/EJE-14-0537 10.1017/S0317167100021132 |
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| Keywords | Hypokalemia Adrenal adenoma Rhabdomyolysis Primary aldosteronism |
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| Publisher | Elsevier B.V Department of Endocrinology, Ba?gc?lar Training and Research Hospital, Istanbul, Turkey%Department of Radiology, Erciyes University Medical School, Kayseri, Turkey%Department of Endocrinology, Kayseri Training and Research Hospital, Kayseri, Turkey%Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey Wolters Kluwer Medknow Publications |
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| References_xml | – volume: 123 start-page: 547 year: 2013 end-page: 551 ident: bib19 article-title: Primary aldosteronism: a new insight into pathogenesis, diagnosis, and treatment in hypertensive patients publication-title: Pol Arch Med Wewn contributor: fullname: Kokot – volume: 373 start-page: 60 year: 2015 end-page: 72 ident: bib7 article-title: An integrated view of potassium homeostasis publication-title: N Engl J Med contributor: fullname: Wingo – volume: 31 start-page: 72 year: 2007 end-page: 79 ident: bib11 article-title: Primary hyperaldosteronism secondary to unilateral adrenal hyperplasia: an unusual cause of surgically correctable hypertension. 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| Title | Primary hyperaldosteronism presenting with rhabdomyolysis in emergency room – Case report |
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