Transcriptome changes in DM1 patients’ tissues are governed by the RNA interference pathway

Myotonic dystrophy type 1 (DM1) is a multisystemic disease caused by pathogenic expansions of CTG repeats. The expanded repeats are transcribed to long RNA and induce cellular toxicity. Recent studies suggest that the CUG repeats are processed by the RNA interference (RNAi) pathway to generate small...

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Bibliographic Details
Published inFrontiers in molecular biosciences Vol. 9; p. 955753
Main Authors Braun, Maya, Shoshani, Shachar, Tabach, Yuval
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 19.08.2022
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