Cancer stem cell-immune cell crosstalk in the tumor microenvironment for liver cancer progression

• Published in: Frontiers of medicine Vol. 18; no. 3; pp. 430 - 445
• Main Authors: Ma, Yue, Lv, Hongwei, Xing, Fuxue, Xiang, Wei, Wu, Zixin, Feng, Qiyu, Wang, Hongyang, Yang, Wen
• Format: Journal Article
• Language: English
• Published: Beijing Higher Education Press 01.06.2024; Springer Nature B.V
• Subjects: Immunotherapy; Liver cancer; Medicine; Medicine & Public Health; Review; immune cell; liver cancer; cancer stem cell; immunotherapy

Crosstalk between cancer cells and the immune microenvironment is determinant for liver cancer progression. A tumor subpopulation called liver cancer stem cells (CSCs) significantly accounts for the initiation, metastasis, therapeutic resistance, and recurrence of liver cancer. Emerging evidence dem...