Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis

• Published in: Clinical rheumatology Vol. 23; no. 1; pp. 35 - 39
• Main Authors: Yu, Min-Chien, Huang, Chung-Ming, Wu, Mei-Chen, Wu, Jer-Yuarn, Tsai, Fuu-Jen
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.02.2004
• Subjects: Arthritis, Rheumatoid - ethnology; Arthritis, Rheumatoid - genetics; Arthritis, Rheumatoid - pathology; Asian Continental Ancestry Group - ethnology; Associations; ATP-Binding Cassette Sub-Family B Member 2; ATP-Binding Cassette Transporters - genetics; ATP-Binding Cassette, Sub-Family B, Member 3; Chromosome Mapping; DNA Primers - chemistry; Drug therapy; Female; Gene Frequency; Genes; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Rheumatoid arthritis; Taiwan - epidemiology
• ISSN: 0770-3198; 1434-9949
• DOI: 10.1007/s10067-003-0769-3

The aim of this study was to investigate the association between the polymorphism of transporters associated with antigen processing ( TAP1/TAP2) genes and rheumatoid arthritis in Chinese patients. A total of 100 RA patients and 99 healthy control subjects were enrolled. Analyses with polymerase cha...