Brucine-Loaded Ethosomal Gel: Design, Optimization, and Anti-inflammatory Activity

• Published in: AAPS PharmSciTech Vol. 22; no. 8; p. 269
• Main Authors: Abdallah, Marwa H., Lila, Amr S. Abu, Unissa, Rahamat, Elsewedy, Heba S., Elghamry, Hanaa A., Soliman, Mahmoud S.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 11.11.2021
• Subjects: Biochemistry; Biomedical and Life Sciences; Biomedicine; Biotechnology; Pharmacology/Toxicology; Pharmacy; Research Article; Transdermal drug delivery; Brucine; Anti-inflammatory; Ethosomes; Gel

Brucine, one of the natural medications obtained from Nux vomica seeds, is used as an anti-inflammatory drug. Several investigations were performed to overcome its drawbacks, which will affect significantly its pharmaceutical formulation. The goal of the current investigation was to design, optimize...