Acute humoral rejection in an infant without risk factors after heart transplantation
Graft rejection is the most common factor that limits graft survival after transplantation. During infancy, the humoral immune system is partially suppressed and humoral rejection of a cardiac allograft has not been reported in the absence of risk factors such as prior transplantation, blood transfu...
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Published in | Journal of cardiac surgery Vol. 33; no. 2; pp. 126 - 128 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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United States
01.02.2018
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Subjects | |
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Abstract | Graft rejection is the most common factor that limits graft survival after transplantation. During infancy, the humoral immune system is partially suppressed and humoral rejection of a cardiac allograft has not been reported in the absence of risk factors such as prior transplantation, blood transfusions, ventricular assist devices, and elevation of panel reactive antibodies. We present a case of an infant with dilated cardiomyopathy who developed multiple episodes of acute humoral rejection after heart transplantation in the absence of risk factors. |
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AbstractList | Graft rejection is the most common factor that limits graft survival after transplantation. During infancy, the humoral immune system is partially suppressed and humoral rejection of a cardiac allograft has not been reported in the absence of risk factors such as prior transplantation, blood transfusions, ventricular assist devices, and elevation of panel reactive antibodies. We present a case of an infant with dilated cardiomyopathy who developed multiple episodes of acute humoral rejection after heart transplantation in the absence of risk factors. |
Author | Fraser, Charles D. Mery, Carlos M. Heinle, Jeffrey S. Marcano, Juan Zea‐Vera, Rodrigo Binsalamah, Ziyad M. Tunuguntla, Hari Kearney, Debra L. |
Author_xml | – sequence: 1 givenname: Ziyad M. orcidid: 0000-0001-9767-7007 surname: Binsalamah fullname: Binsalamah, Ziyad M. email: ziyadmss@gmail.com organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 2 givenname: Juan surname: Marcano fullname: Marcano, Juan organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 3 givenname: Rodrigo surname: Zea‐Vera fullname: Zea‐Vera, Rodrigo organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 4 givenname: Hari surname: Tunuguntla fullname: Tunuguntla, Hari organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 5 givenname: Debra L. surname: Kearney fullname: Kearney, Debra L. organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 6 givenname: Jeffrey S. surname: Heinle fullname: Heinle, Jeffrey S. organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 7 givenname: Charles D. surname: Fraser fullname: Fraser, Charles D. organization: Texas Children's Hospital—Baylor College of Medicine – sequence: 8 givenname: Carlos M. surname: Mery fullname: Mery, Carlos M. organization: Texas Children's Hospital—Baylor College of Medicine |
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Cites_doi | 10.1016/j.healun.2006.11.011 10.1016/j.transci.2017.07.005 10.1016/j.healun.2012.03.009 10.5858/2007-131-1169-UOCTP |
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Keywords | heart transplantation humoral rejection dilated cardiomyopathy |
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References | 2012; 31 2014 2007; 26 2007; 131 2017; 56 Tan (10.1111/jocs.13532-BIB0002|jocs13532-cit-0002) 2007; 131 Cozzi (10.1111/jocs.13532-BIB0005|jocs13532-cit-0005) 2017; 56 Casarez (10.1111/jocs.13532-BIB0004|jocs13532-cit-0004) 2007; 26 Rasmussen (10.1111/jocs.13532-BIB0006|jocs13532-cit-0006) 2014 Casarez (10.1111/jocs.13532-BIB0001|jocs13532-cit-0001) 2007; 26 Everitt (10.1111/jocs.13532-BIB0003|jocs13532-cit-0003) 2012; 31 |
References_xml | – volume: 31 start-page: 686 year: 2012 end-page: 693 article-title: Biopsy‐diagnosed antibody‐mediated rejection based on the proposed International Society for Heart and Lung Transplantation working formulation is associated with adverse cardiovascular outcomes after pediatric heart transplant publication-title: J Heart Lung Transplant – volume: 131 start-page: 1169 year: 2007 end-page: 1191 article-title: Update on cardiac transplantation pathology publication-title: Arch Pathol Lab Med – volume: 56 start-page: 498 year: 2017 end-page: 505 article-title: The mechanisms of rejection in solid organ transplantation publication-title: Transfus Apher Sci – start-page: 1283 year: 2014 end-page: 1292 – volume: 26 start-page: 114 year: 2007 end-page: 119 article-title: Humoral rejection in pediatric orthotopic heart transplantation publication-title: J Heart Lung Transplant – volume: 26 start-page: 114 year: 2007 ident: 10.1111/jocs.13532-BIB0001|jocs13532-cit-0001 article-title: Humoral rejection in pediatric orthotopic heart transplantation publication-title: J Heart Lung Transplant doi: 10.1016/j.healun.2006.11.011 contributor: fullname: Casarez – volume: 26 start-page: 114 year: 2007 ident: 10.1111/jocs.13532-BIB0004|jocs13532-cit-0004 article-title: Humoral rejection in pediatric orthotopic heart transplantation publication-title: J Heart Lung Transplant doi: 10.1016/j.healun.2006.11.011 contributor: fullname: Casarez – volume: 56 start-page: 498 year: 2017 ident: 10.1111/jocs.13532-BIB0005|jocs13532-cit-0005 article-title: The mechanisms of rejection in solid organ transplantation publication-title: Transfus Apher Sci doi: 10.1016/j.transci.2017.07.005 contributor: fullname: Cozzi – volume: 31 start-page: 686 year: 2012 ident: 10.1111/jocs.13532-BIB0003|jocs13532-cit-0003 article-title: Biopsy-diagnosed antibody-mediated rejection based on the proposed International Society for Heart and Lung Transplantation working formulation is associated with adverse cardiovascular outcomes after pediatric heart transplant publication-title: J Heart Lung Transplant doi: 10.1016/j.healun.2012.03.009 contributor: fullname: Everitt – volume: 131 start-page: 1169 year: 2007 ident: 10.1111/jocs.13532-BIB0002|jocs13532-cit-0002 article-title: Update on cardiac transplantation pathology publication-title: Arch Pathol Lab Med doi: 10.5858/2007-131-1169-UOCTP contributor: fullname: Tan – start-page: 1283 volume-title: Operative Pediatric Surgery year: 2014 ident: 10.1111/jocs.13532-BIB0006|jocs13532-cit-0006 contributor: fullname: Rasmussen |
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SubjectTerms | dilated cardiomyopathy heart transplantation humoral rejection |
Title | Acute humoral rejection in an infant without risk factors after heart transplantation |
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