NAD+ metabolism and therapeutic strategies in cardiovascular diseases

• Published in: Atherosclerosis plus Vol. 57; pp. 1 - 12
• Main Authors: Shi, Chongxu, Wen, Zhaozhi, Yang, Yihang, Shi, Linsheng, Liu, Dong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2024; Elsevier
• Subjects: Atherosclerosis; Cardiovascular diseases; Nicotinamide adenine dinucleotide; Review; Vascular disorder; Nicotinamide adenine dinucleotide; Cardiovascular diseases; Vascular disorder; Atherosclerosis

Nicotinamide adenine dinucleotide (NAD+) is a central and pleiotropic metabolite involved in cellular energy metabolism, cell signaling, DNA repair, and protein modifications. Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Metabolic stress and aging directly affect the card...