Clinical, metabolic and endocrine parameters in response to metformin in obese women with polycystic ovary syndrome: a randomized, double-blind and placebo-controlled trial

• Published in: Hormone and metabolic research Vol. 35; no. 2; p. 86
• Main Authors: Chou, K H, von Eye Corleta, H, Capp, E, Spritzer, P M
• Format: Journal Article
• Language: English
• Published: Germany 01.02.2003
• Subjects: Adolescent; Adult; Blood Pressure - drug effects; Body Mass Index; Double-Blind Method; Female; Follicle Stimulating Hormone - blood; Humans; Hypoglycemic Agents - therapeutic use; Lipids - blood; Lipoproteins - blood; Luteinizing Hormone - blood; Metformin - therapeutic use; Obesity - blood; Obesity - complications; Obesity - drug therapy; Placebos; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - drug therapy; Sex Hormone-Binding Globulin - metabolism; Testosterone - blood

There is still some controversy concerning the effects of metformin in the treatment of Polycystic Ovary Syndrome (PCOS). The aim of this study was to asses the effect of metformin on clinical, metabolic and hormone parameters in obese women with PCOS. Thirty obese, non-diabetic women with PCOS rece...