Influence of ABCB11 and HNF4α genes on daclatasvir plasma concentration: preliminary pharmacogenetic data from the Kineti-C study - Cusato, Jessica; De Nicolò, Amedeo; Boglione, Lucio; Favata, Fabio; Ariaudo, Alessandra; Mornese Pinna, Simone; Guido, Federica; Avataneo, Valeria; Carcieri, Chiara; Cariti, Giuseppe; Di Perri, Giovanni; D’Avolio, Antonio (Journal of antimicrobial chemotherapy, 2017)
Keywords: Adult; Alleles; Antiviral Agents - blood; Antiviral Agents - therapeutic use; ATP Binding Cassette Subfamily B Member 11 - drug effects; ATP Binding Cassette Subfamily B Member 11 - genetics; Female; Genotype; Hepacivirus - drug effects; Hepatitis C - drug therapy; Hepatitis C - genetics; Hepatitis C - virology; Hepatocyte Nuclear Factor 4 - drug effects; Hepatocyte Nuclear Factor 4 - genetics; Humans; Imidazoles - blood; Imidazoles - therapeutic use; Linear Models; Male; Middle Aged; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction