The CAV1 Gene 3' Untranslated Region Single Nucleotide Polymorphisms Are Associated with the Risk of Pulmonary Hypertension in Chinese Han Chronic Obstructive Pulmonary Patients

• Published in: Genetic testing and molecular biomarkers Vol. 23; no. 9; p. 634
• Main Authors: Li, Minjing, Cai, Wanru, Chen, Ye, Dong, Lei
• Format: Journal Article
• Language: English
• Published: United States 01.09.2019
• Subjects: 3' Untranslated Regions; Aged; Alleles; Asian Continental Ancestry Group; Caveolin 1 - blood; Caveolin 1 - genetics; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Heterozygote; Humans; Hypertension, Pulmonary - genetics; Male; MicroRNAs - blood; Middle Aged; Polymorphism, Single Nucleotide; Pulmonary Disease, Chronic Obstructive - complications; Risk Factors; caveolin-1; hsa-miR-451; single nucleotide polymorphisms; pulmonary hypertension; chronic obstructive pulmonary disease

Caveolin-1, which is encoded by the caveolin-1 ( ) gene, plays an important role in the development of pulmonary hypertension (PH). The purpose of this study was to determine the relationship between 3' untranslated region (UTR) single nucleotide polymorphisms (SNPs) of the gene and the risk of...